Anti-ABCA3 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ABCA3 Antibody (CSB-PA859942ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

ATP-binding cassette sub-family A member 3 Antibody,ABC-C transporter Antibody,ATP-binding cassette transporter 3 Antibody,ATP-binding cassette 3 Antibody,ABCA3 Antibody,ABC3 Antibody

More alternative names for the antibody
ABC-C transporter antibody|Abca3 antibody|ABCA3_HUMAN antibody|ATP-binding cassette 3 antibody|ATP-binding cassette sub-family A member 3 antibody|ATP-binding cassette transporter 3 antibody
Anti-ABCA3 antibody – N-terminal (ab187755)
Close sc-48442|sc-48444|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-ABCA3 Antibody

Catalogue No.

CSB-PA859942ESR1HU

Reactivity

Human

Immunogen

Recombinant human ATP-binding cassette sub-family A member 3 protein (43-203AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

191 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:21( Human), Entrez Gene:27410( Mouse), Entrez Gene:302973( Rat), Omim:601615( Human), SwissProt:Q99758( Human), SwissProt:Q8R420( Mouse), Unigene:26630( Human), Unigene:239470( Mouse)

Protein function

Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol.

Protein tissue specificity

Highly expressed in lung, followed by brain, pancreas, skeletal muscle and heart. Weakly expressed in placenta, kidney and liver. Also expressed in medullary thyroid carcinoma cells (MTC) and in C-cell carcinoma.

Involvement in disease

Pulmonary surfactant metabolism dysfunction 3 (SMDP3) [MIM:610921]: A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the ABC transporter superfamily. ABCA family. Multifunctional polypeptide with two homologous halves, each containing a hydrophobic membrane-anchoring domain and an ATP binding cassette (ABC) domain.

Protein cellular localization

Membrane ; Multi-pass membrane protein .

Research area

All research areas>Transport and Trafficking>ABC
(View all antibody categories related to Transport and Trafficking)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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