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Rabbit Anti-ABCC11 Antibody (CSB-PA846641ESR1HU)
Supplier: CUSABIO BIOTECH CO.
ATP-binding cassette sub-family C member 11 Antibody,Multidrug resistance-associated protein 8 Antibody,ABCC11 Antibody,MRP8 AntibodyMore alternative names for the antibody
ABCC 11 antibody|ATP binding cassette protein C11 antibody|ATP binding cassette sub family C (CFTR/MRP) member 11 antibody|ATP binding cassette sub family C member 11 antibody|ATP binding cassette transporter MRP8 antibody|ATP binding cassette transporter sub family C member 11 antibody|EWWD antibody|MRP8 antibody|Multi resistance protein 8 antibody|Multidrug resistance associated protein 8 antibody|OTTHUMP00000164191 antibody|WW antibody
Anti-ABCC11 antibody [M8I-74] (ab91452)
Anti-ABCC11 antibody [M8I-74] (ab91452)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human ATP-binding cassette sub-family C member 11 protein (1-170AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=85320" target="_blank">Entrez Gene:85320( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/607040" target="_blank">Omim:607040( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q96J66" target="_blank">SwissProt:Q96J66( Human)</a>
|Protein function|| |
Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides (PubMed:12764137, PubMed:15537867). Enhances the cellular extrusion of cAMP and cGMP (PubMed:12764137, PubMed:15537867). Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate (PubMed:15537867, PubMed:25896536). Probably functions to secrete earwax (PubMed:16444273, PubMed:19383836). Required for the secretion of components contributing to axillary odor formation (PubMed:19710689). .
|Protein tissue specificity|| |
Expressed in ceruminous apocrine gland (at protein level) (PubMed:19383836, PubMed:19710689). Expressed in many tissues. Not expressed in kidney, spleen and colon. Highly expressed in breast cancer. Expressed at moderate levels in normal breast and testis and at very low levels in liver, brain and placenta. .
|Protein sequence and domain|| |
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
|Protein cellular localization|| |
Cell membrane ; Multi-pass membrane protein . Vacuole membrane . Cytoplasmic vesicle membrane .
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Transport-and-Trafficking/">Transport and Trafficking</a>><a href="https://antibodyplus.com/product-tag/ABC/">ABC</a><br><a href="https://antibodyplus.com/product-tag/Transport-and-Trafficking/"> (View all antibody categories related to Transport and Trafficking)</a>
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|Product type|| |
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