Anti-ABHD5 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-ABHD5 Antibody (CSB-PA819884ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Abhydrolase domain-containing protein 5 Antibody,Lipid droplet-binding protein CGI-58 Antibody,ABHD5 Antibody,NCIE2 Antibody,CGI-58 Antibody

More alternative names for the antibody
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 antibody|ABHD5 antibody|ABHD5_HUMAN antibody|Abhydrolase domain containing 5 antibody|Abhydrolase domain containing protein 5 antibody|Abhydrolase domain-containing protein 5 antibody|CDS antibody|CGI 58 antibody|CGI58 antibody|CGI58 protein antibody|IECN2 antibody|Lipid droplet-binding protein CGI-58 antibody|MGC8731 antibody|NCIE2 antibody
Anti-Abhd5 antibody (ab73551)
Close sc-100468|sc-102285|sc-393949|sc-377270|sc-376931|sc-292546|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-ABHD5 Antibody

Catalogue No.

CSB-PA819884ESR1HU

Reactivity

Human

Immunogen

Recombinant human 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 protein (1-349AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

39 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:51099( Human), Entrez Gene:67469( Mouse), Entrez Gene:497624( Pig), Entrez Gene:316122( Rat), Entrez Gene:100125355( Sheep), Omim:604780( Human), SwissProt:Q8WTS1( Human), SwissProt:Q9DBL9( Mouse), SwissProt:Q5EE05( Pig), SwissProt:Q6QA69( Rat), Unigene:19385( Human), Unigene:280254( Mouse), Unigene:12459( Rat)

Protein function

Lysophosphatidic acid acyltransferase which functions in phosphatidic acid biosynthesis (PubMed:18606822). May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2 (PubMed:16679289). Involved in keratinocyte differentiation (PubMed:18832586). Regulates lipid droplet fusion (By similarity). .

Protein tissue specificity

Widely expressed in various tissues, including lymphocytes, liver, skeletal muscle and brain. Expressed by upper epidermal layers and dermal fibroblasts in skin, hepatocytes and neurons (at protein level). .

Involvement in disease

Chanarin-Dorfman syndrome (CDS) [MIM:275630]: An autosomal recessive inborn error of lipid metabolism with multisystemic accumulation of triglycerides although plasma concentrations are normal. Clinical characteristics are congenital generalized ichthyosis, vacuolated leukocytes, hepatomegaly, myopathy, cataracts, neurosensory hearing loss and developmental delay. The disorder presents at birth with generalized, fine, white scaling of the skin and a variable degree of erythema resembling non-bullous congenital ichthyosiform erythroderma. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily. The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

Protein cellular localization

Cytoplasm . Lipid droplet . Note=Colocalized with PLIN and ADRP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA (By similarity). .

Research area

All research areas>Synthesis and Degradation>ABHD
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!