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Rabbit Anti-ABHD5 Antibody (CSB-PA819884ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Abhydrolase domain-containing protein 5 Antibody,Lipid droplet-binding protein CGI-58 Antibody,ABHD5 Antibody,NCIE2 Antibody,CGI-58 AntibodyMore alternative names for the antibody
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 antibody|ABHD5 antibody|ABHD5_HUMAN antibody|Abhydrolase domain containing 5 antibody|Abhydrolase domain containing protein 5 antibody|Abhydrolase domain-containing protein 5 antibody|CDS antibody|CGI 58 antibody|CGI58 antibody|CGI58 protein antibody|IECN2 antibody|Lipid droplet-binding protein CGI-58 antibody|MGC8731 antibody|NCIE2 antibody
Anti-Abhd5 antibody (ab73551)
Anti-Abhd5 antibody (ab73551)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 protein (1-349AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:51099( Human), Entrez Gene:67469( Mouse), Entrez Gene:497624( Pig), Entrez Gene:316122( Rat), Entrez Gene:100125355( Sheep), Omim:604780( Human), SwissProt:Q8WTS1( Human), SwissProt:Q9DBL9( Mouse), SwissProt:Q5EE05( Pig), SwissProt:Q6QA69( Rat), Unigene:19385( Human), Unigene:280254( Mouse), Unigene:12459( Rat)
|Protein function|| |
Lysophosphatidic acid acyltransferase which functions in phosphatidic acid biosynthesis (PubMed:18606822). May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2 (PubMed:16679289). Involved in keratinocyte differentiation (PubMed:18832586). Regulates lipid droplet fusion (By similarity). .
|Protein tissue specificity|| |
Widely expressed in various tissues, including lymphocytes, liver, skeletal muscle and brain. Expressed by upper epidermal layers and dermal fibroblasts in skin, hepatocytes and neurons (at protein level). .
|Involvement in disease|| |
Chanarin-Dorfman syndrome (CDS) [MIM:275630]: An autosomal recessive inborn error of lipid metabolism with multisystemic accumulation of triglycerides although plasma concentrations are normal. Clinical characteristics are congenital generalized ichthyosis, vacuolated leukocytes, hepatomegaly, myopathy, cataracts, neurosensory hearing loss and developmental delay. The disorder presents at birth with generalized, fine, white scaling of the skin and a variable degree of erythema resembling non-bullous congenital ichthyosiform erythroderma. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily. The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.
|Protein cellular localization|| |
Cytoplasm . Lipid droplet . Note=Colocalized with PLIN and ADRP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA (By similarity). .
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CUSABIO BIOTECH CO.
|Product type|| |
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