Anti-ACVR1 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ACVR1 Antibody (CSB-PA001257ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Activin receptor type I Antibody,ACTR-I Antibody,Activin receptor-like kinase 2 Antibody,ALK-2 Antibody,Serine/threonine-protein kinase receptor R1 Antibody,SKR1 Antibody,TGF-B superfamily receptor type I Antibody,TSR-I Antibody,ACVR1 Antibody,ACVRLK2 Antibody

More alternative names for the antibody
Activin A receptor type I antibody|Activin A receptor type II like kinase 2 antibody|Activin receptor type I antibody|Activin receptor type-1 antibody|Activin receptor-like kinase 2 antibody|ACTR-I antibody|ACTRI antibody|Acvr1 antibody|ACVR1_HUMAN antibody|ACVR1A antibody|ACVRLK2 antibody|ALK 2 antibody|ALK-2 antibody|ALK2 antibody|FOP antibody|Hydroxyalkyl protein kinase antibody|Serine/threonine-protein kinase receptor R1 antibody|SKR1 antibody|TGF-B superfamily receptor type I antibody|TGFB superfamily receptor type I antibody|TSR-I antibody|TSRI antibody
Anti-Activin Receptor Type IA antibody (ab115301)
Close sc-374523|sc-31295|sc-25449|sc-5671|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-ACVR1 Antibody

Catalogue No.

CSB-PA001257ESR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Activin receptor type-1 protein (20-125AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

57 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:90( Human), Entrez Gene:11477( Mouse), Entrez Gene:79558( Rat), Omim:102576( Human), SwissProt:Q04771( Human), SwissProt:P37172( Mouse), SwissProt:P80201( Rat), Unigene:470316( Human), Unigene:689( Mouse), Unigene:87899( Rat)

Protein function

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis (By similarity). .

Protein tissue specificity

Expressed in normal parenchymal cells, endothelial cells, fibroblasts and tumor-derived epithelial cells.

Involvement in disease

Fibrodysplasia ossificans progressiva (FOP) [MIM:135100]: A rare autosomal dominant connective tissue disorder resulting in skeletal malformations and progressive extraskeletal ossification. Heterotopic ossification begins in childhood and can be induced by trauma or may occur without warning. Bone formation is episodic and progressive, leading to a debilitating ankylosis of all major joints of the axial and appendicular skeleton, rendering movement impossible. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Research area

All research areas>Membrane Receptors>ACTR
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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