Anti-ADAM19 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ADAM19 Antibody (CSB-PA880929ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Disintegrin and metalloproteinase domain-containing protein 19 Antibody,ADAM 19 Antibody,Meltrin-beta Antibody,Metalloprotease and disintegrin dendritic antigen marker Antibody,MADDAM Antibody,ADAM19 Antibody,MLTNB Antibody,FKSG34 Antibody

More alternative names for the antibody
A disintegrin and metalloproteinase domain 19 (meltrin beta) antibody|A disintegrin and metalloproteinase domain 19 antibody|ADAM 19 antibody|ADAM metallopeptidase domain 19 antibody|Disintegrin and metalloproteinase domain containing protein 19 antibody|FKSG 34 antibody|FKSG34 antibody|MADDAM antibody|Meltrin beta antibody|Metalloprotease and disintegrin dentritic antigen marker antibody|Metalloprotease disintegrin meltrin beta antibody|MLTN B antibody|MLTNB antibody
Anti-ADAM19 antibody (ab191457)
Close sc-25988|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-ADAM19 Antibody

Catalogue No.

CSB-PA880929ESR1HU

Reactivity

Human

Immunogen

Recombinant human Disintegrin and metalloproteinase domain-containing protein 19 protein (203-460AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

104 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:8728( Human), Entrez Gene:11492( Mouse), Entrez Gene:303068( Rat), Omim:603640( Human), SwissProt:Q9H013( Human), SwissProt:O35674( Mouse), Unigene:89940( Mouse)

Protein function

Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity). .

Protein tissue specificity

Expressed in many normal organ tissues and several cancer cell lines.

Protein sequence and domain

The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.

Protein post-translational modifications

The precursor is cleaved by a furin endopeptidase. .

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Research area

All research areas>Synthesis and Degradation>ADAM
(View all antibody categories related to Synthesis and Degradation)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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