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Rabbit Anti-ADAM33 Antibody (CSB-PA861182ESR2HU)
Supplier: CUSABIO BIOTECH CO.
ADAM 33 Antibody,ADAM33 Antibody,C20orf153 AntibodyMore alternative names for the antibody
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Disintegrin and metalloproteinase domain-containing protein 33 protein (140-420AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein tissue specificity|| |
Expressed in all tissues, except liver, with high expression in placenta, lung, spleen and veins. .
|Involvement in disease|| |
Asthma (ASTHMA) [MIM:600807]: The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with wheezing due to spasmodic contraction of the bronchi. . Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
|Protein sequence and domain|| |
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
|Protein post-translational modifications|| |
The precursor is cleaved by a furin endopeptidase. .
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein.
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CUSABIO BIOTECH CO.
|Product type|| |
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