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Rabbit Anti-AIMP1 Antibody (CSB-PA618638DSR1HU)
Supplier: CUSABIO BIOTECH CO.
Multisynthase complex auxiliary component p43 Antibody,EMAP-2 Antibody,Endothelial monocyte-activating polypeptide II Antibody,EMAP-II Antibody,Small inducible cytokine subfamily E member 1 Antibody,AIMP1 Antibody,EMAP2 Antibody, SCYE1 AntibodyMore alternative names for the antibody
AIMP 1 antibody|Aimp1 antibody|AIMP1/p43 antibody|AIMP1_HUMAN antibody|Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 antibody|ARS interacting multifunctional protein 1 antibody|EMAP 2 antibody|EMAP-2 antibody|EMAP-II antibody|EMAP2 antibody|EMAPII antibody|Endothelial monocyte activating polypeptide 2 antibody|Endothelial monocyte activating polypeptide antibody|Endothelial monocyte-activating polypeptide 2 antibody|Endothelial monocyte-activating polypeptide II antibody|HLD3 antibody|Multisynthase complex auxiliary component p43 antibody|Multisynthetase complex auxiliary component p43 antibody|OTTHUMP00000219673 antibody|p43 antibody|Scye 1 antibody|Scye1 antibody|Scye1, formerly antibody|Small inducible cytokine subfamily E member 1 antibody|Small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) antibody|Small inducible cytokine subfamily E, member 1, formerly antibody
Anti-EMAP II antibody [546-2] (ab15693)
Anti-EMAP II antibody [546-2] (ab15693)
Recommended applications: ELISA, WB, IHC, IP
Recommended dilution: Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 protein (25-180AA)
ELISA, WB, IHC, IP
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7. .
|Involvement in disease|| |
Leukodystrophy, hypomyelinating, 3 (HLD3) [MIM:260600]: A severe autosomal recessive hypomyelinating leukodystrophy characterized by early infantile onset of global developmental delay, lack of development, lack of speech acquisition, and peripheral spasticity associated with decreased myelination in the central nervous system. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein post-translational modifications|| |
Cleaved by caspase-7 in response to apoptosis to produce EMAP-II.
|Protein cellular localization|| |
Nucleus. Cytoplasm, cytosol. Cytoplasmic vesicle, secretory vesicle . Secreted . Endoplasmic reticulum . Golgi apparatus . Note=Enriched in secretory vesicles of pancreatic alpha cells and secreted from the pancreas in response to low glucose levels (By similarity). Also secreted in response to hypoxia and both apoptotic and necrotic cell death. .
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CUSABIO BIOTECH CO.
|Product type|| |
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