Anti-AIMP2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-AIMP2 Antibody (CSB-PA819153ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Multisynthase complex auxiliary component p38 Antibody,Protein JTV-1 Antibody,AIMP2 Antibody,JTV1 Antibody

More alternative names for the antibody
Aimp2 antibody|AIMP2_HUMAN antibody|Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 antibody|Aminoacyl tRNA synthetase complex interacting multifunctional protein 2 antibody|ARS interacting multi functional protein 2 antibody|JTV 1 antibody|JTV 1 protein antibody|JTV1 antibody|JTV1 gene antibody|Multisynthase complex auxiliary component p38 antibody|Multisynthetase complex auxiliary component p38 antibody|P38 antibody|PRO0992 antibody|Protein JTV 1 antibody|Protein JTV-1 antibody|tRNA SYNTHETASE COFACTOR p38 antibody
Anti-AIMP2/p38 antibody (ab101840)
Close sc-160454|sc-160455|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-AIMP2 Antibody

Catalogue No.

CSB-PA819153ESR1HU

Reactivity

Human

Immunogen

Recombinant human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein (141-320AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

35 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:7965( Human), Entrez Gene:231872( Mouse), Entrez Gene:288480( Rat), Omim:600859( Human), SwissProt:Q13155( Human), SwissProt:Q8R010( Mouse), SwissProt:Q32PX2( Rat), Unigene:301613( Human), Unigene:728827( Human), Unigene:200499( Mouse), Unigene:162097( Rat)

Protein function

Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor. .

Protein post-translational modifications

Phosphorylated on serine residues in response to UV irradiation. .; Ubiquitinated by PARK2, leading to its degradation by the proteasome. Mutant PARK2 fails to ubiquitinate AIMP2 efficiently, allowing its accumulation which may contribute to neurodegeneration associated with Parkinson disease. .

Protein cellular localization

Cytoplasm, cytosol . Nucleus . Note=Following DNA damage, dissociates from the aminoacyl-tRNA synthase complex and translocates from the cytoplasm to the nucleus. .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!