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Rabbit Anti-AKAP5 Antibody (CSB-PA001527ESR2HU)
Supplier: CUSABIO BIOTECH CO.
AKAP-5 Antibody,A-kinase anchor protein 79 kDa Antibody,AKAP 79 Antibody,H21 Antibody,cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein Antibody,AKAP5 Antibody,AKAP79 AntibodyMore alternative names for the antibody
A kinase (PRKA) anchor protein 5 antibody|A kinase anchor protein 5 antibody|A kinase anchor protein 79kDa antibody|A kinase anchoring protein 75/79 antibody|A-kinase anchor protein 5 antibody|A-kinase anchor protein 79 kDa antibody|AKAP 5 antibody|AKAP 75 antibody|AKAP 79 antibody|AKAP-5 antibody|Akap5 antibody|AKAP5_HUMAN antibody|AKAP75 antibody|AKAP79 antibody|cAMP dependent protein kinase regulatory subunit II high affinity binding protein antibody|cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein antibody|H21 antibody
Anti-AKAP5 antibody (ab64851)
Anti-AKAP5 antibody (ab64851)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human A-kinase anchor protein 5 protein (1-270AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9495" target="_blank">Entrez Gene:9495( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/604688" target="_blank">Omim:604688( Human)</a>, <a href="http://www.uniprot.org/uniprot/P24588" target="_blank">SwissProt:P24588( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=656683" target="_blank">Unigene:656683( Human)</a>
|Protein function|| |
May anchor the PKA protein to cytoskeletal and/or organelle-associated proteins, targeting the signal carried by cAMP to specific intracellular effectors. Association with to the beta2-adrenergic receptor (beta2-AR) not only regulates beta2-AR signaling pathway, but also the activation by PKA by switching off the beta2-AR signaling cascade.
|Protein tissue specificity|| |
Predominantly in the cerebral cortex and the postsynaptic densities of the forebrain, and to a lesser extent in adrenal medulla, lung and anterior pituitary.
|Protein sequence and domain|| |
RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.; The N-terminal region, which is highly basic, is required for interaction with calmodulin.
|Protein post-translational modifications|| |
Palmitoylation at Cys-36 and Cys-129 plays a key role in targeting to lipid rafts. .
|Protein cellular localization|| |
Membrane ; Lipid-anchor . Note=Associates with lipid rafts.
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Signaling-Intermediates/">Signaling Intermediates</a>><a href="https://antibodyplus.com/product-tag/AKAP/">AKAP</a><br><a href="https://antibodyplus.com/product-tag/Signaling-Intermediates/"> (View all antibody categories related to Signaling Intermediates)</a>
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CUSABIO BIOTECH CO.
|Product type|| |
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