Anti-AKAP5 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-AKAP5 Antibody (CSB-PA001527ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

AKAP-5 Antibody,A-kinase anchor protein 79 kDa Antibody,AKAP 79 Antibody,H21 Antibody,cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein Antibody,AKAP5 Antibody,AKAP79 Antibody

More alternative names for the antibody
A kinase (PRKA) anchor protein 5 antibody|A kinase anchor protein 5 antibody|A kinase anchor protein 79kDa antibody|A kinase anchoring protein 75/79 antibody|A-kinase anchor protein 5 antibody|A-kinase anchor protein 79 kDa antibody|AKAP 5 antibody|AKAP 75 antibody|AKAP 79 antibody|AKAP-5 antibody|Akap5 antibody|AKAP5_HUMAN antibody|AKAP75 antibody|AKAP79 antibody|cAMP dependent protein kinase regulatory subunit II high affinity binding protein antibody|cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein antibody|H21 antibody
Anti-AKAP5 antibody (ab64851)
Close sc-135826|sc-17772|sc-10764|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-AKAP5 Antibody

Catalogue No.

CSB-PA001527ESR2HU

Reactivity

Human

Immunogen

Recombinant human A-kinase anchor protein 5 protein (1-270AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

47 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:9495( Human), Omim:604688( Human), SwissProt:P24588( Human), Unigene:656683( Human)

Protein function

May anchor the PKA protein to cytoskeletal and/or organelle-associated proteins, targeting the signal carried by cAMP to specific intracellular effectors. Association with to the beta2-adrenergic receptor (beta2-AR) not only regulates beta2-AR signaling pathway, but also the activation by PKA by switching off the beta2-AR signaling cascade.

Protein tissue specificity

Predominantly in the cerebral cortex and the postsynaptic densities of the forebrain, and to a lesser extent in adrenal medulla, lung and anterior pituitary.

Protein sequence and domain

RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.; The N-terminal region, which is highly basic, is required for interaction with calmodulin.

Protein post-translational modifications

Palmitoylation at Cys-36 and Cys-129 plays a key role in targeting to lipid rafts. .

Protein cellular localization

Membrane ; Lipid-anchor . Note=Associates with lipid rafts.

Research area

All research areas>Signaling Intermediates>AKAP
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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