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Rabbit Anti-AKR1C4 Antibody (CSB-PA001545ESR2HU)
Supplier: CUSABIO BIOTECH CO.
3-alpha-HSD1 Antibody,3-alpha-hydroxysteroid dehydrogenase type I Antibody,Chlordecone reductase Antibody,CDR Antibody,Dihydrodiol dehydrogenase 4 Antibody,DD-4 Antibody,DD4 Antibody,HAKRA Antibody,AKR1C4 Antibody,CHDR AntibodyMore alternative names for the antibody
3 alpha HSD1 antibody|3-alpha-HSD1 antibody|3-alpha-hydroxysteroid dehydrogenase type I antibody|AK1C4_HUMAN antibody|AKR1C4 antibody|Aldo keto reductase family 1 member C4 antibody|Aldo-keto reductase family 1 member C4 antibody|CDR antibody|Chlordecone reductase antibody|DD-4 antibody|DD4 antibody|Dihydrodiol dehydrogenase 4 antibody|HAKRA antibody
Anti-HSD3a antibody (ab54606)
Anti-HSD3a antibody (ab54606)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Aldo-keto reductase family 1 member C4 protein (1-323AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1109" target="_blank">Entrez Gene:1109( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/600451" target="_blank">Omim:600451( Human)</a>, <a href="http://www.uniprot.org/uniprot/P17516" target="_blank">SwissProt:P17516( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=567245" target="_blank">Unigene:567245( Human)</a>
|Protein function|| |
Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
|Protein tissue specificity|| |
Liver specific. .
|Involvement in disease|| |
46,XY sex reversal 8 (SRXY8) [MIM:614279]: A disorder of sex development. Affected individuals have a 46,XY karyotype but present as phenotypically normal females. . Note=The gene represented in this entry may act as a disease modifier. A splicing mutation resulting in loss of AKR1C4 exon 2 has been found in affected individuals carrying a causative mutation in AKR1C2 (PubMed:21802064). These patients manifest a more severe disease phenotype than individuals only carrying mutations in AKR1C2. .
|Protein sequence and domain|| |
Belongs to the aldo/keto reductase family.
|Protein post-translational modifications|| |
The N-terminus is blocked.
|Protein cellular localization|| |
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Synthesis-and-Degradation/">Synthesis and Degradation</a>><a href="https://antibodyplus.com/product-tag/DD/">DD</a><br><a href="https://antibodyplus.com/product-tag/Synthesis-and-Degradation/"> (View all antibody categories related to Synthesis and Degradation)</a>
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CUSABIO BIOTECH CO.
|Product type|| |
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