Anti-ALAS2 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ALAS2 Antibody (CSB-PA001560ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

ALAS-E Antibody,5-aminolevulinic acid synthase 2 Antibody,Delta-ALA synthase 2 Antibody,Delta-aminolevulinate synthase 2 Antibody,ALAS2 Antibody,ALASE Antibody, ASB Antibody

More alternative names for the antibody
5 aminolevulinate synthase erythroid specific antibody|5 aminolevulinate synthase 2 antibody|5 aminolevulinate synthase 5 aminolevulinate synthase 2 antibody|5 aminolevulinate synthase erythroid specific mitochondrial antibody|5 aminolevulinic acid synthase 2 antibody|5 aminolevulinic acid synthase antibody|5-aminolevulinate synthase antibody|5-aminolevulinic acid synthase 2 antibody|Alas 2 antibody|ALAS antibody|ALAS E antibody|ALAS, erythroid antibody|ALAS-E antibody|Alas2 antibody|ALASE antibody|Aminolevulinate delta synthase 2 antibody|Aminolevulinic acid synthase 2, erythroid antibody|ANH1 antibody|ASB antibody|Delta ALA synthase 2 antibody|Delta ALA synthetase antibody|Delta aminolevulinate synthase 2 antibody|Delta aminolevulinate synthase antibody|Delta-ALA synthase 2 antibody|Delta-aminolevulinate synthase 2 antibody|Erythroid specific ALAS antibody|erythroid-specific antibody|FLJ93603 antibody|HEM0_HUMAN antibody|mitochondrial antibody|OTTHUMP00000023388 antibody|OTTHUMP00000023389 antibody|OTTMUSP00000020679 antibody|RP23-338A17.1 antibody|SIDBA1 antibody|XLDPP antibody|XLEPP antibody|XLSA antibody
Anti-ALAS2 antibody [EPR15112(B)] – C-terminal (ab184964)
Close sc-166739|sc-50529|sc-50530|sc-32334|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-ALAS2 Antibody

Catalogue No.

CSB-PA001560ESR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human 5-aminolevulinate synthase, erythroid-specific, mitochondrial protein (50-320AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

64 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:212( Human), Entrez Gene:11656( Mouse), Entrez Gene:25748( Rat), Omim:301300( Human), SwissProt:P22557( Human), SwissProt:P08680( Mouse), SwissProt:Q63147( Rat), Unigene:522666( Human), Unigene:555936( Human), Unigene:302724( Mouse), Unigene:226279( Rat), Unigene:32517( Rat)

Protein tissue specificity

Erythroid specific.

Involvement in disease

Anemia, sideroblastic, 1 (SIDBA1) [MIM:300751]: A form of sideroblastic anemia that shows a variable hematologic response to pharmacologic doses of pyridoxine. Sideroblastic anemia is characterized by anemia of varying severity, hypochromic peripheral erythrocytes, systemic iron overload secondary to chronic ineffective erythropoiesis, and the presence of bone marrow ringed sideroblasts. Sideroblasts are characterized by iron-loaded mitochondria clustered around the nucleus. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Erythropoietic protoporphyria, X-linked dominant (XLDPT) [MIM:300752]: A form of porphyria. Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. XLDPT is characterized biochemically by a high proportion of zinc-protoporphyrin in erythrocytes, in which a mismatch between protoporphyrin production and the heme requirement of differentiating erythroid cells leads to overproduction of protoporphyrin in amounts sufficient to cause photosensitivity and liver disease. . Note=The disease is caused by mutations affecting the gene represented in this entry. Gain of function mutations in ALS2 are responsible for XLDPT, but they can also be a possible aggravating factor in congenital erythropoietic porphyria and other erythropoietic disorders caused by mutations in other genes (PubMed:21309041). .

Protein sequence and domain

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Protein cellular localization

Mitochondrion matrix .

Research area

All research areas>Signaling Intermediates>ALAS
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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