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Rabbit Anti-ALKBH8 Antibody (CSB-PA842644ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Probable alpha-ketoglutarate-dependent dioxygenase ABH8 Antibody,S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8 Antibody,tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8 Antibody,ALKBH8 Antibody,ABH8 AntibodyMore alternative names for the antibody
4930562C03Rik antibody|8030431D03Rik antibody|9430088N01Rik antibody|ABH8 antibody|alkB alkylation repair homolog 8 (E. coli) antibody|alkB alkylation repair homolog 8 antibody|AlkB homologue 8 antibody|ALKB8_HUMAN antibody|ALKBH8 antibody|Alkylated DNA repair protein alkB homolog 8 antibody|FLJ38204 antibody|MGC10235 antibody|OTTHUMP00000211286 antibody|OTTHUMP00000211287 antibody|Probable alpha-ketoglutarate-dependent dioxygenase ABH8 antibody|RGD1304687 antibody|S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8 antibody|tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8 antibody
Anti-ALKBH8 antibody (ab113512)
Anti-ALKBH8 antibody (ab113512)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant humanAlkylated DNA repair protein alkB homolog 8 protein (1-230AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:91801( Human), Entrez Gene:67667( Mouse), Entrez Gene:366783( Rat), Omim:613306( Human), SwissProt:Q96BT7( Human), SwissProt:Q80Y20( Mouse), Unigene:503763( Human), Unigene:116968( Mouse), Unigene:440994( Mouse)
|Protein function|| |
Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain (PubMed:20123966, PubMed:20308323). Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA (PubMed:20123966, PubMed:20308323). Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys)(PubMed:20308323). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine; has a preference for tRNA(Gly) (PubMed:21285950). Required for normal survival after DNA damage (PubMed:20308323). May inhibit apoptosis and promote cell survival and angiogenesis (PubMed:19293182). .
|Protein tissue specificity|| |
Widely expressed, with highest expression in spleen, followed by pancreas and lung. .
|Protein sequence and domain|| |
Belongs to the alkB family.
|Protein cellular localization|| |
Cytoplasm . Nucleus . Note=Predominantly cytoplasmic. .
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CUSABIO BIOTECH CO.
|Product type|| |
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