Anti-ALKBH8 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ALKBH8 Antibody (CSB-PA842644ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Probable alpha-ketoglutarate-dependent dioxygenase ABH8 Antibody,S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8 Antibody,tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8 Antibody,ALKBH8 Antibody,ABH8 Antibody

More alternative names for the antibody
4930562C03Rik antibody|8030431D03Rik antibody|9430088N01Rik antibody|ABH8 antibody|alkB alkylation repair homolog 8 (E. coli) antibody|alkB alkylation repair homolog 8 antibody|AlkB homologue 8 antibody|ALKB8_HUMAN antibody|ALKBH8 antibody|Alkylated DNA repair protein alkB homolog 8 antibody|FLJ38204 antibody|MGC10235 antibody|OTTHUMP00000211286 antibody|OTTHUMP00000211287 antibody|Probable alpha-ketoglutarate-dependent dioxygenase ABH8 antibody|RGD1304687 antibody|S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8 antibody|tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8 antibody
Anti-ALKBH8 antibody (ab113512)
Close sc-101882|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-ALKBH8 Antibody

Catalogue No.

CSB-PA842644ESR1HU

Reactivity

Human

Immunogen

Recombinant humanAlkylated DNA repair protein alkB homolog 8 protein (1-230AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

75 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:91801( Human), Entrez Gene:67667( Mouse), Entrez Gene:366783( Rat), Omim:613306( Human), SwissProt:Q96BT7( Human), SwissProt:Q80Y20( Mouse), Unigene:503763( Human), Unigene:116968( Mouse), Unigene:440994( Mouse)

Protein function

Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain (PubMed:20123966, PubMed:20308323). Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA (PubMed:20123966, PubMed:20308323). Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys)(PubMed:20308323). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine; has a preference for tRNA(Gly) (PubMed:21285950). Required for normal survival after DNA damage (PubMed:20308323). May inhibit apoptosis and promote cell survival and angiogenesis (PubMed:19293182). .

Protein tissue specificity

Widely expressed, with highest expression in spleen, followed by pancreas and lung. .

Protein sequence and domain

Belongs to the alkB family.

Protein cellular localization

Cytoplasm . Nucleus . Note=Predominantly cytoplasmic. .

Research area

All research areas>Signaling Intermediates>ALKB
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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