Anti-ALOX15B Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ALOX15B Antibody (CSB-PA001622ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

15-LOX-B Antibody,Arachidonate 15-lipoxygenase B Antibody,15-lipoxygenase 2 Antibody,15-LOX-2 Antibody,Arachidonate 15-lipoxygenase type II Antibody,Linoleate 13-lipoxygenase 15-LOb Antibody,ALOX15B Antibody

More alternative names for the antibody
15 LO 2 antibody|15 LOX 2 antibody|15-lipoxygenase 2 antibody|15-LOX-2 antibody|15-LOX-B antibody|Alox15b antibody|Arachidonate 15 lipoxygenase second type antibody|Arachidonate 15 lipoxygenase type II antibody|Arachidonate 15-lipoxygenase B antibody|Arachidonate 15-lipoxygenase type II antibody|LX15B_HUMAN antibody
Anti-15 Lipoxygenase 2 antibody (ab23691)
Close sc-46048|sc-376871|sc-271290|sc-46049|sc-376795|sc-67142|sc-166387|sc-67143|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-1:2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-ALOX15B Antibody

Catalogue No.

CSB-PA001622ESR2HU

Reactivity

Human

Immunogen

Recombinant human Arachidonate 15-lipoxygenase B protein (1-200AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-1:2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

75 kDa

Purification

Antigen Affinity purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:247( Human), Omim:603697( Human), SwissProt:O15296( Human), Unigene:111256( Human)

Protein function

Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells. .

Protein tissue specificity

Expressed in hair, prostate, lung, ovary, lymph node, spinal cord and cornea. .

Protein sequence and domain

Belongs to the lipoxygenase family. The PLAT domain can bind calcium ions; this promotes association with membranes.

Protein cellular localization

Isoform A: Nucleus. Note=Other isoforms are excluded from the nucleus.; Cytoplasm, cytosol. Cell membrane. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Predominantly cytosolic; becomes enriched at membranes upon calcium binding.

Research area

All research areas>Synthesis and Degradation>LO
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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