Anti-ALS2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ALS2 Antibody (CSB-PA857009ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein Antibody,Amyotrophic lateral sclerosis 2 protein Antibody,ALS2 Antibody,ALS2CR6 Antibody, KIAA1563 Antibody

More alternative names for the antibody
ALS 2 antibody|ALS2 antibody|ALS2_HUMAN antibody|ALS2CR6 antibody|Alsin antibody|ALSJ antibody|Amyotrophic lateral sclerosis 2 (juvenile) antibody|Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 6 antibody|Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein antibody|Amyotrophic lateral sclerosis 2 protein antibody|Amyotrophic lateral sclerosis protein 2 antibody|FLJ31851 antibody|IAHSP antibody|KIAA1563 antibody|MGC87187 antibody|PLSJ antibody
Anti-Als2 antibody [EPR11185] (ab170896)
Close sc-134256|sc-47947|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-ALS2 Antibody

Catalogue No.

CSB-PA857009ESR2HU

Reactivity

Human

Immunogen

Recombinant human Alsin protein (1-280AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

183 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:57679( Human), GenBank:NM_020919( Human), Omim:606352 ( Human), SwissProt:Q96Q42( Human), Unigene:471096( Human), Unigene:621812( Human)

Protein function

May act as a GTPase regulator. Controls survival and growth of spinal motoneurons (By similarity). .

Involvement in disease

Amyotrophic lateral sclerosis 2 (ALS2) [MIM:205100]: A neurodegenerative disorder affecting upper motor neurons in the brain and lower motor neurons in the brain stem and spinal cord, resulting in fatal paralysis. Sensory abnormalities are absent. The pathologic hallmarks of the disease include pallor of the corticospinal tract due to loss of motor neurons, presence of ubiquitin-positive inclusions within surviving motor neurons, and deposition of pathologic aggregates. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors. The disease is inherited in 5-10% of the cases. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Juvenile primary lateral sclerosis (JPLS) [MIM:606353]: A neurodegenerative disorder which is closely related to but clinically distinct from amyotrophic lateral sclerosis. It is a progressive paralytic disorder which results from dysfunction of the upper motor neurons while the lower neurons are unaffected. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Infantile-onset ascending spastic paralysis (IAHSP) [MIM:607225]: Characterized by progressive spasticity and weakness of limbs. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Research area

All research areas>Neurobiology Antibodies>Alsin
(View all antibody categories related to Neurobiology Antibodies)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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