Anti-AMOT Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-AMOT Antibody (CSB-PA001677ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

AMOT Antibody

More alternative names for the antibody
AMOT antibody|AMOT_HUMAN antibody|Angiomotin antibody|Angiomotin p130 isoform antibody|KIAA1071 antibody
Anti-Angiomotin antibody (ab85143)
Close sc-166924|sc-82491|sc-515262|sc-98803|sc-82493|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-AMOT Antibody

Catalogue No.

CSB-PA001677ESR2HU

Reactivity

Human

Immunogen

Recombinant human Angiomotin protein (1-300AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

118 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:154796( Human), Entrez Gene:27494( Mouse), Entrez Gene:300289( Rat), Omim:300410( Human), SwissProt:Q4VCS5( Human), SwissProt:Q8VHG2( Mouse), Unigene:528051( Human), Unigene:100068( Mouse)

Protein function

Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions. .

Protein tissue specificity

Expressed in placenta and skeletal muscle. Found in the endothelial cells of capillaries as well as larger vessels of the placenta. .

Protein sequence and domain

Belongs to the angiomotin family. The coiled coil domain interacts directly with the BAR domain of ARHGAP17.; The angiostatin binding domain (871-1005) allows the binding to angiostatin.

Protein post-translational modifications

Polyubiquitinated by NEDD4, NEDD4L and ITCH, leading to proteasomal degradation. .

Protein cellular localization

Cell junction, tight junction . Note=Localized on the cell surface. May act as a transmembrane protein.

Research area

All research areas>Signaling Intermediates>Angiomotin
(View all antibody categories related to Signaling Intermediates)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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