Anti-ANAPC2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ANAPC2 Antibody (CSB-PA892446DSR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Anaphase-promoting complex subunit 2 Antibody,APC2 Antibody,Cyclosome subunit 2 Antibody,ANAPC2 Antibody,APC2 Antibody,KIAA1406 Antibody

More alternative names for the antibody
anapc2 antibody|Anaphase promoting complex subunit 2 antibody|Anaphase-promoting complex subunit 2 antibody|ANC2_HUMAN antibody|APC2 antibody|Cyclosome subunit 2 antibody|KIAA1406 antibody|OTTHUMP00000022692 antibody|RP11 350O14.5 antibody
Anti-Apc2 antibody [1A6] (ab123855)
Close sc-517022|sc-20984|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-ANAPC2 Antibody

Catalogue No.

CSB-PA892446DSR1HU

Reactivity

Human

Immunogen

Recombinant human Anaphase-promoting complex subunit 2 protein (1-230AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

93 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:29882( Human), Entrez Gene:99152( Mouse), Entrez Gene:296558( Rat), Omim:606946( Human), SwissProt:Q9UJX6( Human), SwissProt:Q8BZQ7( Mouse), Unigene:533262( Human), Unigene:291624( Mouse)

Protein function

Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of ‘Lys-11’-linked polyubiquitin chains and, to a lower extent, the formation of ‘Lys-48’- and ‘Lys-63’-linked polyubiquitin chains. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation. .

Protein sequence and domain

Belongs to the cullin family.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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