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Rabbit Anti-ANTXR1 Antibody (CSB-PA001832ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Tumor endothelial marker 8 Antibody,ANTXR1 Antibody,ATR Antibody, TEM8 AntibodyMore alternative names for the antibody
Anthrax toxin receptor 1 antibody|ANTR1_HUMAN antibody|Antxr1 antibody|ATR antibody|Tumor endothelial marker 8 antibody
Anti-TEM8 antibody (ab21270)
Anti-TEM8 antibody (ab21270)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Anthrax toxin receptor 1 protein (315-564AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:84168( Human), Entrez Gene:69538( Mouse), Entrez Gene:362393( Rat), Omim:606410( Human), SwissProt:Q9H6X2( Human), SwissProt:Q9CZ52( Mouse), SwissProt:Q0PMD2( Rat), Unigene:165859( Human), Unigene:232525( Mouse), Unigene:41192( Rat)
|Protein function|| |
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. .
|Protein tissue specificity|| |
Detected in umbilical vein endothelial cells (at protein level). Highly expressed in tumor endothelial cells. .
|Involvement in disease|| |
Hemangioma, capillary infantile (HCI) [MIM:602089]: A condition characterized by dull red, firm, dome-shaped hemangiomas, sharply demarcated from surrounding skin, usually presenting at birth or occurring within the first two or three months of life. They result from highly proliferative, localized growth of capillary endothelium and generally undergo regression and involution without scarring. . Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.; GAPO syndrome (GAPO) [MIM:230740]: A disease characterized by growth retardation, alopecia, failure of tooth eruption, and progressive optic atrophy in some patients. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the ATR family. Binding to PA occurs through the VWA domain.
|Protein cellular localization|| |
Cell membrane ; Single-pass type I membrane protein . Cell projection, lamellipodium membrane ; Single-pass type I membrane protein . Cell projection, filopodium membrane ; Single-pass type I membrane protein . Note=At the membrane of lamellipodia and at the tip of actin-enriched filopodia. Colocalizes with actin at the base of lamellipodia.
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CUSABIO BIOTECH CO.
|Product type|| |
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