Anti-ANTXR1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ANTXR1 Antibody (CSB-PA001832ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Tumor endothelial marker 8 Antibody,ANTXR1 Antibody,ATR Antibody, TEM8 Antibody

More alternative names for the antibody
Anthrax toxin receptor 1 antibody|ANTR1_HUMAN antibody|Antxr1 antibody|ATR antibody|Tumor endothelial marker 8 antibody
Anti-TEM8 antibody (ab21270)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-ANTXR1 Antibody

Catalogue No.

CSB-PA001832ESR1HU

Reactivity

Human

Immunogen

Recombinant human Anthrax toxin receptor 1 protein (315-564AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

62 kDa

Purification

Antigen Affinity purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:84168( Human), Entrez Gene:69538( Mouse), Entrez Gene:362393( Rat), Omim:606410( Human), SwissProt:Q9H6X2( Human), SwissProt:Q9CZ52( Mouse), SwissProt:Q0PMD2( Rat), Unigene:165859( Human), Unigene:232525( Mouse), Unigene:41192( Rat)

Protein function

Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. .

Protein tissue specificity

Detected in umbilical vein endothelial cells (at protein level). Highly expressed in tumor endothelial cells. .

Involvement in disease

Hemangioma, capillary infantile (HCI) [MIM:602089]: A condition characterized by dull red, firm, dome-shaped hemangiomas, sharply demarcated from surrounding skin, usually presenting at birth or occurring within the first two or three months of life. They result from highly proliferative, localized growth of capillary endothelium and generally undergo regression and involution without scarring. . Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.; GAPO syndrome (GAPO) [MIM:230740]: A disease characterized by growth retardation, alopecia, failure of tooth eruption, and progressive optic atrophy in some patients. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the ATR family. Binding to PA occurs through the VWA domain.

Protein cellular localization

Cell membrane ; Single-pass type I membrane protein . Cell projection, lamellipodium membrane ; Single-pass type I membrane protein . Cell projection, filopodium membrane ; Single-pass type I membrane protein . Note=At the membrane of lamellipodia and at the tip of actin-enriched filopodia. Colocalizes with actin at the base of lamellipodia.

Research area

All research areas>Membrane Receptors>TEM
(View all antibody categories related to Membrane Receptors)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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