Anti-ANTXR2 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ANTXR2 Antibody (CSB-PA001833ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Anthrax toxin receptor 2 Antibody,Capillary morphogenesis gene 2 protein Antibody,CMG-2 Antibody,ANTXR2 Antibody,CMG2 Antibody

More alternative names for the antibody
2310046B19Rik antibody|Anthrax toxin receptor 2 antibody|ANTR2_HUMAN antibody|Antxr2 antibody|AW561899 antibody|Capillary morphogenesis gene 2 protein antibody|Capillary morphogenesis protein 2 antibody|CMG 2 antibody|CMG-2 antibody|CMG2 antibody|FLJ31074 antibody|HFS antibody|ISH antibody|JHF antibody|MGC111533 antibody|MGC45856 antibody
Anti-ANTXR2 antibody [EPR7717] (ab129004)
Close sc-48127|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-ANTXR2 Antibody

Catalogue No.

CSB-PA001833ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Anthrax toxin receptor 2 protein (340-489AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

53 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:118429( Human), Entrez Gene:71914( Mouse), Entrez Gene:305633( Rat), Omim:608041( Human), SwissProt:P58335( Human), SwissProt:Q6DFX2( Mouse), Unigene:162963( Human), Unigene:24842( Mouse), Unigene:229072( Rat)

Protein function

Necessary for cellular interactions with laminin and the extracellular matrix. .

Protein tissue specificity

Expressed in prostate, thymus, ovary, testis, pancreas, colon, heart, kidney, lung, liver, peripheral blood leukocytes, placenta, skeletal muscle, small intestine and spleen. .

Involvement in disease

Hyaline fibromatosis syndrome (HFS) [MIM:228600]: An autosomal recessive syndrome characterized by abnormal growth of hyalinized fibrous tissue usually affecting subcutaneous regions on the scalp, ears, neck, face, hands, and feet. The lesions appear as pearly papules or fleshy nodules. Additional features include gingival hypertrophy, progressive joint contractures resulting in severe limitation of mobility, osteopenia, and osteoporosis. Disease severity is variable. Some individuals manifest symptoms in infancy and have additional visceral or systemic involvement. Hyaline deposits in multiple organs, recurrent infections and intractable diarrhea often lead to early death. Surviving children may suffer from severely reduced mobility due to joint contractures. Other patients have later onset of a milder disorder affecting only the face and digits. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the ATR family. Binding to PA seems to be effected through the VWA domain.

Protein cellular localization

Isoform 1: Cell membrane; Single-pass type I membrane protein. Note=Expressed at the cell surface.; Isoform 2: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Expressed predominantly within the endoplasmic reticulum and not at the plasma membrane.; Isoform 3: Secreted.

Research area

All research areas>Kinases and Phosphatases>ATR
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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