Anti-AP3B1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-AP3B1 Antibody (CSB-PA001874ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

AP-3 complex subunit beta-1 Antibody,Adaptor protein complex AP-3 subunit beta-1 Antibody,Adaptor-related protein complex 3 subunit beta-1 Antibody,Beta-3A-adaptin Antibody,Clathrin assembly protein complex 3 beta-1 large chain Antibody,AP3B1 Antibody,ADTB3A Antibody

More alternative names for the antibody
Adaptor protein complex AP-3 subunit beta-1 antibody|Adaptor protein complex AP3 beta1 subunit antibody|ADTB3 antibody|ADTB3A antibody|AP-3 complex subunit beta-1 antibody|AP3 complex beta1 subunit antibody|AP3B1 antibody|AP3B1_HUMAN antibody|Beta-3A-adaptin antibody|Beta3A adaptin antibody|Clathrin assembly protein complex 3 beta 1 large chain antibody|Clathrin assembly protein complex 3 beta-1 large chain antibody|HPS antibody|PE antibody
Anti-HPS2 antibody – C-terminal (ab197155)
Close sc-517083|sc-69447|sc-13384|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-AP3B1 Antibody

Catalogue No.

CSB-PA001874ESR1HU

Reactivity

Human

Immunogen

Recombinant human AP-3 complex subunit beta-1 protein (895-1094AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

121 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:767602( Cow), Entrez Gene:403459( Dog), Entrez Gene:8546( Human), Entrez Gene:11774( Mouse), Omim:603401( Human), SwissProt:Q32PG1( Cow), SwissProt:Q7YRF1( Dog), SwissProt:O00203( Human), SwissProt:Q9Z1T1( Mouse), Unigene:532091( Human), Unigene:21185( Mouse)

Protein function

Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

Protein tissue specificity

Ubiquitously expressed. .

Involvement in disease

Hermansky-Pudlak syndrome 2 (HPS2) [MIM:608233]: A form of Hermansky-Pudlak syndrome, a genetically heterogeneous autosomal recessive disorder characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS. HPS2 differs from the other forms of HPS in that it includes immunodeficiency in its phenotype and patients with HPS2 have an increased susceptibility to infections. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the adaptor complexes large subunit family.

Protein post-translational modifications

Phosphorylated on serine residues. .

Protein cellular localization

Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Golgi apparatus . Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. .

Research area

All research areas>Transport and Trafficking>Adaptin Related Adapter Protein
(View all antibody categories related to Transport and Trafficking)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!