Anti-APOBEC3C Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-APOBEC3C Antibody (CSB-PA889097ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

A3C Antibody,APOBEC1-like Antibody,Phorbolin I Antibody,APOBEC3C Antibody,APOBEC1L Antibody,PBI Antibody

More alternative names for the antibody
A3C antibody|ABC3C_HUMAN antibody|APOBEC1 like antibody|APOBEC1-like antibody|APOBEC1L antibody|APOBEC3C antibody|Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C antibody|ARDC2 antibody|ARDC4 antibody|ARP5 antibody|bK150C2.3 antibody|DNA dC >dU editing enzyme APOBEC 3C antibody|MGC19485 antibody|PBI antibody|Phorbolin I antibody|Phorbolin I protein antibody|Probable DNA dC dU editing enzyme APOBEC 3C antibody|Probable DNA dC->dU-editing enzyme APOBEC-3C antibody
Anti-APOBEC3C antibody [EPR13417] (ab181356)
Close sc-367880|sc-46732|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-APOBEC3C Antibody

Catalogue No.

CSB-PA889097ESR2HU

Reactivity

Human

Immunogen

Recombinant human DNA dC->dU-editing enzyme APOBEC-3C protein (1-190AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

22 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:27350( Human), Omim:607750( Human), SwissProt:Q9NRW3( Human), Unigene:441124( Human)

Protein function

DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV), hepatitis B virus (HBV), herpes simplex virus 1 (HHV-1) and Epstein-Barr virus (EBV) and may inhibit the mobility of LTR and non-LTR retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. .

Protein tissue specificity

Expressed in spleen, testes, peripherical blood lymphocytes, heart, thymus, prostate and ovary. .

Protein sequence and domain

Belongs to the cytidine and deoxycytidylate deaminase family.

Protein cellular localization

Nucleus. Cytoplasm.

Research area

All research areas>Transcription Regulators>APOBEC
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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