Anti-ASH2L Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ASH2L Antibody (CSB-PA883363ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

ASH2-like protein Antibody,ASH2L Antibody,ASH2L1 Antibody

More alternative names for the antibody
ASH 2 antibody|Ash2 (absent small or homeotic) like antibody|Ash2 (absent, small, or homeotic) like (Drosophila) antibody|ASH2 antibody|ASH2 LIKE antibody|ASH2 like protein antibody|ASH2-like protein antibody|Ash2l antibody|ASH2L_HUMAN antibody|ASH2L1 antibody|ASH2L2 antibody|Bre 2 antibody|Bre2 antibody|Discs 2-like antibody|Drosophila absent, small, or homeotic antibody|Drosophila ASH2-like antibody|Set1/Ash2 histone methyltransferase complex subunit ASH2 antibody
Anti-ASH2L antibody [2046D2a] (ab50699)
Close sc-81184|sc-27283|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-ASH2L Antibody

Catalogue No.

CSB-PA883363ESR1HU

Reactivity

Human

Immunogen

Recombinant human Set1/Ash2 histone methyltransferase complex subunit ASH2 protein (329-628AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

68 kDa

Purification

Antigen Affinity purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:9070( Human), Entrez Gene:23808( Mouse), Entrez Gene:290829( Rat), Omim:604782( Human), SwissProt:Q9UBL3( Human), SwissProt:Q91X20( Mouse), Unigene:521530( Human), Unigene:27706( Mouse), Unigene:219095( Rat)

Protein function

Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates ‘Lys-4’ of histone H3, but not if the neighboring ‘Lys-9’ residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at ‘Lys-4’ of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis. .

Protein tissue specificity

Ubiquitously expressed. Predominantly expressed in adult heart and testis and fetal lung and liver, with barely detectable expression in adult lung, liver, kidney, prostate, and peripheral leukocytes. .

Protein post-translational modifications

Both monomethylated and dimethylated on arginine residues in the C-terminus. Arg-296 is the major site. Methylation is not required for nuclear localization, nor for MLL complex integrity or maintenance of global histone H3K4me3 levels. .

Protein cellular localization

Nucleus .

Research area

All research areas>Transcription Regulators>ASH
(View all antibody categories related to Transcription Regulators)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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