Anti-ATG4C Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ATG4C Antibody (CSB-PA836199ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

AUT-like 3 cysteine endopeptidase Antibody,Autophagin-3 Antibody,Autophagy-related cysteine endopeptidase 3 Antibody,Autophagy-related protein 4 homolog C Antibody,ATG4C Antibody,APG4C Antibody, AUTL1 Antibody,AUTL3 Antibody

More alternative names for the antibody
APG4 autophagy 4 homolog C (S. cerevisiae) antibody|Cysteine protease ATG4C antibody|EC 3.4.22 antibody|FLJ14867 antibody|OTTHUMP00000010715 antibody
Anti-ATG4C antibody – C-terminal (ab191705)
Close sc-163708|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-ATG4C Antibody

Catalogue No.

CSB-PA836199ESR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Cysteine protease ATG4C protein (259-458AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

52 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:84938( Human), Entrez Gene:242557( Mouse), Entrez Gene:313391( Rat), Omim:611339( Human), SwissProt:Q96DT6( Human), SwissProt:Q811C2( Mouse), Unigene:7353( Human), Unigene:241663( Mouse), Unigene:23378( Rat)

Protein function

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. .

Protein tissue specificity

Highly expressed in skeletal muscle, heart, liver and testis. .

Protein sequence and domain

Belongs to the peptidase C54 family.

Protein cellular localization

Cytoplasm .

Research area

All research areas>Synthesis and Degradation>Atg
(View all antibody categories related to Synthesis and Degradation)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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