Anti-ATXN10 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ATXN10 Antibody (CSB-PA883357ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Ataxin-10 Antibody,Brain protein E46 homolog Antibody,Spinocerebellar ataxia type 10 protein Antibody,ATXN10 Antibody,SCA10 Antibody

More alternative names for the antibody
Ataxin 10 antibody|Ataxin-10 antibody|ATX10_HUMAN antibody|Atxn10 antibody|Brain protein E46 homolog antibody|E46L antibody|FLJ37990 antibody|HUMEEP antibody|Like mouse brain protein E46 antibody|OTTHUMP00000197383 antibody|SCA10 antibody|Spinocerebellar ataxia 10 antibody|Spinocerebellar ataxia type 10 protein antibody
Anti-ATXN10 antibody – C-terminal (ab199824)
Close sc-271233|sc-99058|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-ATXN10 Antibody

Catalogue No.

CSB-PA883357ESR1HU

Reactivity

Human

Immunogen

Recombinant human Ataxin-10 protein (346-475AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

53 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:470238( Chimpanzee), Entrez Gene:101140528( Gorilla), Entrez Gene:25814( Human), Entrez Gene:713805( Rhesus monkey), Omim:611150( Human), SwissProt:Q9UBB4( Human), Unigene:475125( Human)

Protein function

Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. .

Protein tissue specificity

Expressed in the central nervous system. .

Involvement in disease

Spinocerebellar ataxia 10 (SCA10) [MIM:603516]: Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA10 is an autosomal dominant cerebellar ataxia (ADCA). . Note=The disease is caused by mutations affecting the gene represented in this entry.; Note=Defects in ATXN1 may be a cause of nephronophthisis a chronic tubulo-interstitial nephropathy that leads to anemia, polyuria, polydipsia, isosthenuria and death in uremia. .

Protein sequence and domain

Belongs to the ataxin-10 family.

Protein cellular localization

Cytoplasm, perinuclear region .

Research area

All research areas>Signaling Intermediates>Ataxin
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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