Anti-AZU1 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-AZU1 Antibody (CSB-PA002485ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Cationic antimicrobial protein CAP37 Antibody,Heparin-binding protein Antibody,HBP Antibody,AZU1 Antibody

More alternative names for the antibody
Azu 1 antibody|AZU1 antibody|Azurocidin antibody|CAP37 antibody|CAP7_HUMAN antibody|Cationic antimicrobial protein 37 antibody|Cationic antimicrobial protein CAP37 antibody|HBP antibody|Heparin binding protein antibody|Heparin-binding protein antibody|HUMAZUR antibody|Neutrophil azurocidin antibody
Anti-Azurocidin antibody [EPR9503] (ab181989)
Close sc-33129|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-AZU1 Antibody

Catalogue No.

CSB-PA002485ESR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Azurocidin protein (27-251AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

26 kDa

Purification

Antigen Affinity purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:566( Human), Omim:162815( Human), SwissProt:P20160( Human), Unigene:72885( Human)

Protein function

This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G. .

Protein sequence and domain

Belongs to the peptidase S1 family. Elastase subfamily.

Protein post-translational modifications

Cleavage of the N-terminal propeptide which is composed of 7 amino acids occurs in two steps. The initial cleavage of 5 amino acids is followed by the cleavage of a dipeptide to produce the mature form. .

Protein cellular localization

Cytoplasmic granule membrane ; Peripheral membrane protein ; Cytoplasmic side . Note=Localizes to azurophil granules of neutrophil granulocytes. Also called primary granules, these specialized lysosomes of the neutrophil formed early during promyelocyte development store antibacterial proteins and peptides. .

Research area

All research areas>Lymphocyte Signaling>Azurocidin
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!