No products in the cart.
Rabbit Anti-BCAS3 Antibody (CSB-PA872507ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Breast carcinoma-amplified sequence 3Imported Antibody,GAOB1 Antibody,BCAS3 AntibodyMore alternative names for the antibody
1500019F07Rik antibody|2610028P08Rik antibody|AU021018 antibody|BC028339 antibody|BCAS3 antibody|BCAS3_HUMAN antibody|Breast carcinoma-amplified sequence 3 antibody|FLJ20128 antibody|GAOB1 antibody|K20D4 antibody|MAAB antibody|Maab1 protein antibody|MGC4973 antibody|rudhira antibody
Anti-BCAS3 antibody (ab106637)
Anti-BCAS3 antibody (ab106637)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Breast carcinoma-amplified sequence 3 protein (689-928AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation (By similarity). Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin. .
|Protein tissue specificity|| |
Expressed in stomach, liver, lung, kidney, prostate, testis, thyroid gland, adrenal gland, brain, heart, skeletal muscle, colon, spleen, small intestine, placenta, blood leukocyte and mammary epithelial cells. Expressed in undifferentiated ES cells. Expressed in blood islands and nascent blood vessels derived from differentiated ES cells into embryoid bodies (BD). Expressed in endothelial cells. Not detected in brain. Expressed in brain tumors (at protein level). Expressed in brain. Highly expressed in breast cancers and in glioma cell lines. .
|Involvement in disease|| |
Note=A chromosomal aberration involving BCAS3 has been found in some breast carcinoma cell lines. Translocation t(17;20)(q23;q13) with BCAS4.
|Protein sequence and domain|| |
Belongs to the BCAS3 family. Has been proposed to contain 7 WD repeats. This prediction could not be reproduced.
|Protein cellular localization|| |
Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Note=Localizes in the cytoplasm in stationary cells. Translocates from the cytoplasm to the leading edge in motile cells. Colocalizes with microtubules and intermediate filaments in both stationary and motile cells (By similarity). Associates with chromatin. Recruited to estrogen receptor-induced promoters in a PELP1-dependent manner. .
AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.
CUSABIO BIOTECH CO.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: