Anti-BCAS3 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-BCAS3 Antibody (CSB-PA872507ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Breast carcinoma-amplified sequence 3Imported Antibody,GAOB1 Antibody,BCAS3 Antibody

More alternative names for the antibody
1500019F07Rik antibody|2610028P08Rik antibody|AU021018 antibody|BC028339 antibody|BCAS3 antibody|BCAS3_HUMAN antibody|Breast carcinoma-amplified sequence 3 antibody|FLJ20128 antibody|GAOB1 antibody|K20D4 antibody|MAAB antibody|Maab1 protein antibody|MGC4973 antibody|rudhira antibody
Anti-BCAS3 antibody (ab106637)
Close sc-365131|sc-98360|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-BCAS3 Antibody

Catalogue No.

CSB-PA872507ESR1HU

Reactivity

Human

Immunogen

Recombinant human Breast carcinoma-amplified sequence 3 protein (689-928AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

101 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:54828( Human), Entrez Gene:192197( Mouse), Entrez Gene:363662( Rat), Omim:607470( Human), SwissProt:Q9H6U6( Human), SwissProt:Q8CCN5( Mouse), Unigene:655028( Human)

Protein function

Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation (By similarity). Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin. .

Protein tissue specificity

Expressed in stomach, liver, lung, kidney, prostate, testis, thyroid gland, adrenal gland, brain, heart, skeletal muscle, colon, spleen, small intestine, placenta, blood leukocyte and mammary epithelial cells. Expressed in undifferentiated ES cells. Expressed in blood islands and nascent blood vessels derived from differentiated ES cells into embryoid bodies (BD). Expressed in endothelial cells. Not detected in brain. Expressed in brain tumors (at protein level). Expressed in brain. Highly expressed in breast cancers and in glioma cell lines. .

Involvement in disease

Note=A chromosomal aberration involving BCAS3 has been found in some breast carcinoma cell lines. Translocation t(17;20)(q23;q13) with BCAS4.

Protein sequence and domain

Belongs to the BCAS3 family. Has been proposed to contain 7 WD repeats. This prediction could not be reproduced.

Protein cellular localization

Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Note=Localizes in the cytoplasm in stationary cells. Translocates from the cytoplasm to the leading edge in motile cells. Colocalizes with microtubules and intermediate filaments in both stationary and motile cells (By similarity). Associates with chromatin. Recruited to estrogen receptor-induced promoters in a PELP1-dependent manner. .

Research area

All research areas>Transport and Trafficking>BCAS
(View all antibody categories related to Transport and Trafficking)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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