Anti-BIN1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-BIN1 Antibody (CSB-PA002700ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Amphiphysin II Antibody,Amphiphysin-like protein Antibody,Box-dependent myc-interacting protein 1 Antibody,Bridging integrator 1 Antibody,BIN1 Antibody,AMPHL Antibody

More alternative names for the antibody
AMPH 2 antibody|AMPH2 antibody|Amphiphysin 2 antibody|Amphiphysin II antibody|Amphiphysin like protein antibody|amphiphysin-like antibody|Amphiphysin-like protein antibody|AMPHL antibody|Bin1 antibody|BIN1_HUMAN antibody|Box Dependant MYC Interacting Protein 1 antibody|Box-dependent myc-interacting protein 1 antibody|Bridging integrator 1 antibody|DKFZp547F068 antibody|MGC10367 antibody|MGC105358 antibody|Myc box dependent interacting protein 1 antibody|Myc box-dependent-interacting protein 1 antibody|SH3P9 antibody
Anti-BIN1 antibody [EPR13463] (ab182562)
Close sc-23918|sc-136316|sc-13575|sc-74486|sc-74487|sc-30099|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-BIN1 Antibody

Catalogue No.

CSB-PA002700ESR1HU

Reactivity

Human

Immunogen

Recombinant human Myc box-dependent-interacting protein 1 protein (414-593AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

64 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:274( Human), Omim:601248( Human), SwissProt:O00499( Human), Unigene:193163( Human)

Protein function

May be involved in regulation of synaptic vesicle endocytosis. May act as a tumor suppressor and inhibits malignant cell transformation.

Protein tissue specificity

Ubiquitous. Highest expression in the brain and muscle. Isoform IIA is expressed only in the brain where it is concentrated in axon initial segments and nodes of Ranvier. Isoform BIN1 is widely expressed with highest expression in skeletal muscle. .

Involvement in disease

Myopathy, centronuclear, 2 (CNM2) [MIM:255200]: A congenital muscle disorder characterized by progressive muscular weakness and wasting involving mainly limb girdle, trunk, and neck muscles. It may also affect distal muscles. Weakness may be present during childhood or adolescence or may not become evident until the third decade of life. Ptosis is a frequent clinical feature. The most prominent histopathologic features include high frequency of centrally located nuclei in muscle fibers not secondary to regeneration, radial arrangement of sarcoplasmic strands around the central nuclei, and predominance and hypotrophy of type 1 fibers. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein post-translational modifications

Phosphorylated by protein kinase C. .

Protein cellular localization

Isoform BIN1: Nucleus.; Isoform IIA: Cytoplasm.

Research area

All research areas>Transport and Trafficking>Amphiphysin
(View all antibody categories related to Transport and Trafficking)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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