Anti-BLOC1S2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-BLOC1S2 Antibody (CSB-PA754307ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Biogenesis of lysosome-related organelles complex 1 subunit 2 Antibody,BLOC-1 subunit 2 Antibody,Centrosome-associated protein Antibody,BLOC1S2 Antibody,BLOS2 Antibody,CEAP Antibody

More alternative names for the antibody
BL1S2_HUMAN antibody|BLOC-1 subunit 2 antibody|Bloc1s2 antibody|BLOS2 antibody|Centrosome-associated protein antibody|RP11 316M21.4 antibody
Anti-BLOC1S2 antibody (ab174929)
Close sc-161392|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-BLOC1S2 Antibody

Catalogue No.

CSB-PA754307ESR1HU

Reactivity

Human

Immunogen

Recombinant human Biogenesis of lysosome-related organelles complex 1 subunit 2 protein (44-142AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

15 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:282991( Human), Entrez Gene:73689( Mouse), Omim:609768( Human), SwissProt:Q6QNY1( Human), SwissProt:Q9CWG9( Mouse), Unigene:34906( Human), Unigene:124685( Mouse)

Protein function

Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes (PubMed:15102850, PubMed:17182842). In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension (By similarity). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167). May play a role in cell proliferation (PubMed:15381421). .

Protein tissue specificity

Isoform 1 and isoform 2 are widely expressed. Expressed in various malignant tumor tissues (at protein level). .

Protein sequence and domain

Belongs to the BLOC1S2 family.

Protein cellular localization

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Lysosome membrane . Note=Localizes to the centrosomes in a microtubule-dependent manner. .

Research area

All research areas>Signaling Intermediates>BLOS
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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