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Rabbit Anti-BLOC1S6 Antibody (CSB-PA890745DSR2HU)
Supplier: CUSABIO BIOTECH CO.
Biogenesis of lysosome-related organelles complex 1 subunit 6 Antibody,BLOC-1 subunit 6 Antibody,Pallid protein homolog Antibody,Pallidin Antibody,Syntaxin 13-interacting protein Antibody,BLOC1S6 Antibody,PA Antibody,PLDN AntibodyMore alternative names for the antibody
Bloc1s6 antibody|PA antibody|Pallid (mouse) homolog antibody|PALLID antibody|Pallid protein antibody|Pallid protein homolog antibody|Pallidin antibody|Pallidin homolog (mouse) antibody|PLDN antibody|PLDN_HUMAN antibody|Syntaxin 13 binding protein antibody|Syntaxin 13-interacting protein antibody
Anti-Pallidin antibody (ab83349)
Anti-Pallidin antibody (ab83349)
Recommended applications: ELISA, WB, IHC, IP
Recommended dilution: Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Biogenesis of lysosome-related organelles complex 1 subunit 6 protein (1-170AA)
ELISA, WB, IHC, IP
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:614408( Cow), Entrez Gene:26258( Human), Entrez Gene:18457( Mouse), Entrez Gene:317630( Rat), Omim:604310( Human), SwissProt:Q08DU8( Cow), SwissProt:Q9UL45( Human), SwissProt:Q9R0C0( Mouse), SwissProt:Q4V8A6( Rat), Unigene:7037( Human), Unigene:139756( Rat)
|Protein function|| |
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process. .
|Protein tissue specificity|| |
Widely expressed. .
|Involvement in disease|| |
Hermansky-Pudlak syndrome 9 (HPS9) [MIM:614171]: A form of Hermansky-Pudlak syndrome, a genetically heterogeneous autosomal recessive disorder characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the BLOC1S6 family.
|Protein post-translational modifications|| |
|Protein cellular localization|| |
Cytoplasm . Membrane ; Peripheral membrane protein . Note=It can exist as a soluble protein as well as a peripheral membrane protein (PubMed:12019270). .
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CUSABIO BIOTECH CO.
|Product type|| |
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