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Rabbit Anti-BNIP3L Antibody (CSB-PA002767ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Adenovirus E1B19K-binding protein B5 Antibody,BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A Antibody,NIP3-like protein X Antibody,NIP3L Antibody,BNIP3L Antibody,BNIP3A Antibody, BNIP3H Antibody, NIX AntibodyMore alternative names for the antibody
Adenovirus E1B19k binding protein B5 antibody|Adenovirus E1B19K-binding protein B5 antibody|BCL2/adenovirus E1B 19 kd protein interacting protein 3a antibody|BCL2/adenovirus E1B 19 kDa protein interacting protein 3A antibody|BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like antibody|BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A antibody|BCL2/adenovirus E1B 19kDa interacting protein 3 like antibody|BNI3L_HUMAN antibody|BNIP3a antibody|BNIP3H antibody|BNIP3L antibody|BNIP3L protein antibody|NIP3 like protein X antibody|NIP3-like protein X antibody|NIP3L antibody|NIX antibody
Anti-BNIP3L antibody (ab8399)
Anti-BNIP3L antibody (ab8399)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like protein (1-187AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:665( Human), Entrez Gene:12177( Mouse), Entrez Gene:140923( Rat), Omim:605368( Human), SwissProt:O60238( Human), SwissProt:Q9Z2F7( Mouse), Unigene:131226( Human), Unigene:29820( Mouse), Unigene:347081( Mouse), Unigene:827( Rat)
|Protein function|| |
Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor. .
|Protein sequence and domain|| |
Belongs to the NIP3 family.
|Protein post-translational modifications|| |
Undergoes progressive proteolysis to an 11 kDa C-terminal fragment, which is blocked by the proteasome inhibitor lactacystin.
|Protein cellular localization|| |
Nucleus envelope. Endoplasmic reticulum. Mitochondrion outer membrane. Membrane ; Single-pass membrane protein . Note=Colocalizes with SPATA18 at the mitochondrion outer membrane.
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CUSABIO BIOTECH CO.
|Product type|| |
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