Anti-C1QB Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-C1QB Antibody (CSB-PA003638ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

C1QB Antibody

More alternative names for the antibody
C1qb antibody|C1QB_HUMAN antibody|Complement C1q subcomponent subunit B antibody|Complement component 1 q subcomponent B chain antibody|Complement component 1 q subcomponent beta polypeptide antibody|Complement component C1q B chain antibody|Complement subcomponent C1q chain B antibody
Anti-C1QB antibody [EPR2981] (ab92508)
Close sc-27665|sc-27664|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-C1QB Antibody

Catalogue No.

CSB-PA003638ESR1HU

Reactivity

Human

Immunogen

Recombinant human Complement C1q subcomponent subunit B protein (104-253AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

26 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:713( Human), Omim:120570( Human), SwissProt:P02746( Human), Unigene:8986( Human)

Protein function

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

Involvement in disease

Complement component C1q deficiency (C1QD) [MIM:613652]: A disorder caused by impaired activation of the complement classical pathway. It generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein post-translational modifications

Hydroxylated on lysine and proline residues. Hydroxylated lysine residues can be glycosylated. Human C1Q contains up to 68.3 hydroxylysine-galactosylglucose residues and up to 2.5 hydroxylysine-galactose per molecule. Total percentage hydroxylysine residues glycosylated is 86.4%. .

Protein cellular localization

Secreted.

Research area

All research areas>Lymphocyte Signaling>C1q
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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