Anti-CDC5L Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-CDC5L Antibody (CSB-PA858712ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Cdc5-like protein Antibody,Pombe cdc5-related protein Antibody,CDC5L Antibody,KIAA0432 Antibody, PCDC5RP Antibody

More alternative names for the antibody
CDC5 antibody|
Anti-CDC5L antibody [2136C1a] (ab51320)
Close sc-135863|sc-81220|sc-398280|

Recommended applications: ELISA, WB

Recommended dilution: Recommended dilution:WB:1:500-5000

Recommended protocols: check protocols

Name

Anti-CDC5L Antibody

Catalogue No.

CSB-PA858712ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Cell division cycle 5-like protein (563-802AA)

Host

Rabbit

Applications

ELISA, WB

Recommended dilution

Recommended dilution:WB:1:500-5000

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

92 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:988( Human), Entrez Gene:71702( Mouse), Entrez Gene:85434( Rat), Omim:602868( Human), SwissProt:Q99459( Human), SwissProt:Q6A068( Mouse), SwissProt:O08837( Rat), Unigene:485471( Human), Unigene:28270( Mouse), Unigene:54977( Rat)

Protein function

DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). .

Protein tissue specificity

Ubiquitously expressed in both fetal and adult tissues. .

Involvement in disease

Note=A chromosomal aberration involving CDC5L is found in multicystic renal dysplasia. Translocation t(6;19)(p21;q13.1) with USF2.

Protein sequence and domain

Belongs to the CEF1 family.

Protein post-translational modifications

Phosphorylated on serine and threonine residues. Phosphorylation on Thr-411 and Thr-438 is required for CDC5L-mediated mRNA splicing. Has no effect on subcellular location nor on homodimerization. Phosphorylated in vitro by CDK2. Phosphorylation enhances interaction with PPP1R8. .

Protein cellular localization

Nucleus . Nucleus speckle . Cytoplasm . Note=May shuttle between cytoplasm and nucleus. .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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