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Rabbit Anti-CDCP1 Antibody (CSB-PA884474ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Membrane glycoprotein gp140 Antibody,Subtractive immunization M plus HEp3-associated 135 kDa protein Antibody,SIMA135 Antibody,Transmembrane and associated with src kinases Antibody,CD318 Antibody,CDCP1 Antibody,TRASK AntibodyMore alternative names for the antibody
9030022E12Rik antibody|AA409659 antibody|CD 318 antibody|CD_antigen=CD318 antibody|CD318 antibody|CD318 antigen antibody|CDCP 1 antibody|Cdcp1 antibody|CDCP1_HUMAN antibody|CUB domain containing protein 1 antibody|CUB domain-containing protein 1 antibody|E030027H19Rik antibody|FLJ13772 antibody|FLJ22375 antibody|FLJ22969 antibody|Membrane glycoprotein gp140 antibody|MGC31813 antibody|OTTHUMP00000164120 antibody|OTTHUMP00000209568 antibody|RGD1305578 antibody|SIMA 135 antibody|SIMA135 antibody|Subtractive immunization M plus HEp3 associated 135 kDa protein antibody|Subtractive immunization M plus HEp3-associated 135 kDa protein antibody|Transmembrane and associated with src kinases antibody|TRASK antibody
Anti-CDCP1 antibody (ab1377)
Anti-CDCP1 antibody (ab1377)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human CUB domain-containing protein 1 protein (523-836AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis. .
|Protein tissue specificity|| |
Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells. .
|Protein post-translational modifications|| |
Phosphorylated on tyrosine by kinases of the SRC family such as SRC and YES as well as by the protein kinase C gamma/PRKCG. Dephosphorylated by phosphotyrosine phosphatases. Also phosphorylated by suramin, a heparin analog. Tyrosine phosphorylated in response to dissociation of integrin alpha-6 beta-4 from laminin-5. .; N-glycosylated. .; A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding). Another peptide of 80 kDa (p80) is present in cultured keratinocytes probably due to tryptic cleavage at an unidentified site on its N-terminal side. Converted to p80 by plasmin, a trypsin-like protease.
|Protein cellular localization|| |
Isoform 1: Cell membrane ; Single-pass membrane protein . Note=Shedding may also lead to a soluble peptide.; Isoform 3: Secreted.
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CUSABIO BIOTECH CO.
|Product type|| |
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