Anti-CEACAM3 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-CEACAM3 Antibody (CSB-PA005163ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Carcinoembryonic antigen CGM1 Antibody,CD66d Antibody,CEACAM3 Antibody,CD66D Antibody, CGM1 Antibody

More alternative names for the antibody
BGP 1 antibody|CD66a antigen antibody|CD66c antigen antibody|CD66d antibody|CD66d antigen antibody|CEACAM1 antibody|Ceacam3 antibody|CEACAM6 antibody|CEAM3_HUMAN antibody
Anti-CD66a + CD66c + CD66d antibody [YTH71.3] (ab128720)
Close sc-59899|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-CEACAM3 Antibody

Catalogue No.

CSB-PA005163ESR2HU

Reactivity

Human

Immunogen

Recombinant human Carcinoembryonic antigen-related cell adhesion molecule 3 protein (1-135AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

27 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:1084( Human), Entrez Gene:4680( Human), Entrez Gene:634( Human), Omim:109770( Human), Omim:163980( Human), Omim:609142( Human), SwissProt:P13688( Human), SwissProt:P40198( Human), SwissProt:P40199( Human), Unigene:11( Human), Unigene:466814( Human), Unigene:512682( Human)

Protein function

Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis. .

Protein tissue specificity

CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney. .

Protein sequence and domain

Belongs to the immunoglobulin superfamily. CEA family. The cytosolic domain is involved in S100A9 interaction.

Protein post-translational modifications

Tyrosine-phosphorylated in response to microbial binding. Tyr-230 and Tyr-241 are both required for phosphorylation to be detected. .

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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