Anti-CENPK Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-CENPK Antibody (CSB-PA005214ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Centromere protein K Antibody,CENP-K Antibody,Interphase centromere complex protein 37 Antibody,Protein AF-5alpha Antibody,p33 Antibody,CENPK Antibody,ICEN37 Antibody,FKSG14 Antibody

More alternative names for the antibody
AF5 alpha antibody|AF5alpha antibody|B130045K24Rik antibody|BB232189 antibody|C530004N04Rik antibody|CENP K antibody|CENPK antibody|Centromere protein K antibody|Centromeric protein K antibody|FKSG 14 antibody|FKSG14 antibody|ICEN 37 antibody|ICEN37 antibody|Interphase centromere complex protein 37 antibody|Leucine zipper protein FKSG14 antibody|OTTHUMP00000161888 antibody|P33 antibody|Protein AF 5alpha antibody|Protein AF5alpha antibody|Solt antibody|Solzt antibody|SoxLZ/Sox6 binding protein Solt antibody|SoxLZ/Sox6 leucine zipper binding protein antibody
Anti-FKSG14 antibody (ab102653)
Close sc-81831|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-CENPK Antibody

Catalogue No.

CSB-PA005214ESR1HU

Reactivity

Human

Immunogen

Recombinant human Centromere protein K protein (1-269AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

31 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:64105( Human), Entrez Gene:60411( Mouse), Omim:611502( Human), SwissProt:Q9BS16( Human), SwissProt:Q9ESN5( Mouse), Unigene:529778( Human)

Protein function

Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with KNL1 to recruit the NDC80 complex to the outer kinetochore. .

Protein tissue specificity

Detected in several fetal organs with highest levels in fetal liver. In adults, it is weakly expressed in lung and placenta. .

Involvement in disease

Note=Chromosomal aberrations involving CENPK are a cause of acute leukemias. Translocation t(5;11)(q12;q23) with KMT2A/MLL1. .

Protein sequence and domain

Belongs to the CENPK family.

Protein cellular localization

Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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