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Rabbit Anti-CEP120 Antibody (CSB-PA836696ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Centrosomal protein of 120 kDa Antibody,Cep120 Antibody,Coiled-coil domain-containing protein 100 Antibody,CEP120 Antibody,CCDC100 AntibodyMore alternative names for the antibody
CCDC100 antibody|CE120_HUMAN antibody|Centrosomal protein of 120 kDa antibody|Cep120 antibody|Coiled-coil domain-containing protein 100 antibody
Anti-CEP120 antibody (ab178745)
Anti-CEP120 antibody (ab178745)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Centrosomal protein of 120 kDa protein (1-270AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:153241( Human), Entrez Gene:225523( Mouse), Entrez Gene:307302( Rat), SwissProt:Q8N960( Human), SwissProt:Q8N960-3( Human), SwissProt:Q7TSG1( Mouse), Unigene:483209( Human), Unigene:193678( Mouse), Unigene:34326( Rat)
|Protein function|| |
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. Required for centriole duplication and maturation during mitosis and subsequent ciliogenesis (By similarity). .
|Involvement in disease|| |
Short-rib thoracic dysplasia 13 with or without polydactyly (SRTD13) [MIM:616300]: A form of short-rib thoracic dysplasia, a group of autosomal recessive ciliopathies that are characterized by a constricted thoracic cage, short ribs, shortened tubular bones, and a ‘trident’ appearance of the acetabular roof. Polydactyly is variably present. Non-skeletal involvement can include cleft lip/palate as well as anomalies of major organs such as the brain, eye, heart, kidneys, liver, pancreas, intestines, and genitalia. Some forms of the disease are lethal in the neonatal period due to respiratory insufficiency secondary to a severely restricted thoracic cage, whereas others are compatible with life. Disease spectrum encompasses Ellis-van Creveld syndrome, asphyxiating thoracic dystrophy (Jeune syndrome), Mainzer-Saldino syndrome, and short rib-polydactyly syndrome. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the CEP120 family.
|Protein cellular localization|| |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Note=Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo. .
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CUSABIO BIOTECH CO.
|Product type|| |
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