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Rabbit Anti-CEP57 Antibody (CSB-PA769805DSR1HU)
Supplier: CUSABIO BIOTECH CO.
Centrosomal protein of 57 kDa Antibody,Cep57 Antibody,FGF2-interacting protein Antibody,Testis-specific protein 57 Antibody,Translokin Antibody,CEP57 Antibody,KIAA0092 Antibody,TSP57 AntibodyMore alternative names for the antibody
Centrosomal protein 57kDa antibody|Centrosomal protein of 57 kDa antibody|Cep57 antibody|Cep57 protein antibody|CEP57_HUMAN antibody|FGF2 interacting protein antibody|FGF2-interacting protein antibody|KIAA0092 antibody|MVA2 antibody|PIG8 antibody|Proliferation inducing protein 8 antibody|Testis specific protein 57 antibody|Testis-specific protein 57 antibody|Translokin antibody|TSP57 antibody
Anti-CEP57 antibody (ab104010)
Anti-CEP57 antibody (ab104010)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Centrosomal protein of 57 kDa protein (1-240AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:353245( Cow), Entrez Gene:9702( Human), Entrez Gene:74360( Mouse), Entrez Gene:315423( Rat), Omim:607951( Human), SwissProt:Q865V0( Cow), SwissProt:Q86XR8( Human), SwissProt:Q8CEE0( Mouse), SwissProt:B4F7A7( Rat), Unigene:101014( Human), Unigene:157212( Mouse), Unigene:94972( Rat)
|Protein function|| |
Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1. .
|Protein tissue specificity|| |
|Involvement in disease|| |
Mosaic variegated aneuploidy syndrome 2 (MVA2) [MIM:614114]: A severe developmental disorder characterized by mosaic aneuploidies, predominantly trisomies and monosomies, involving multiple different chromosomes and tissues. Affected individuals typically present with severe intrauterine growth retardation and microcephaly. Eye anomalies, mild dysmorphism, variable developmental delay, and a broad spectrum of additional congenital abnormalities and medical conditions may also occur. The risk of malignancy is high, with rhabdomyosarcoma, Wilms tumor and leukemia reported in several cases. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the translokin family. The C-terminal region mediates the interaction with microtubules and is able to nucleate and bundles microtubules in vitro.; The centrosome localization domain (CLD) region mediates the localization to centrosomes and homooligomerization.
|Protein cellular localization|| |
Nucleus . Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
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CUSABIO BIOTECH CO.
|Product type|| |
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