Anti-CEP57 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-CEP57 Antibody (CSB-PA769805DSR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Centrosomal protein of 57 kDa Antibody,Cep57 Antibody,FGF2-interacting protein Antibody,Testis-specific protein 57 Antibody,Translokin Antibody,CEP57 Antibody,KIAA0092 Antibody,TSP57 Antibody

More alternative names for the antibody
Centrosomal protein 57kDa antibody|Centrosomal protein of 57 kDa antibody|Cep57 antibody|Cep57 protein antibody|CEP57_HUMAN antibody|FGF2 interacting protein antibody|FGF2-interacting protein antibody|KIAA0092 antibody|MVA2 antibody|PIG8 antibody|Proliferation inducing protein 8 antibody|Testis specific protein 57 antibody|Testis-specific protein 57 antibody|Translokin antibody|TSP57 antibody
Anti-CEP57 antibody (ab104010)
Close sc-109230|sc-368001|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-CEP57 Antibody

Catalogue No.

CSB-PA769805DSR1HU

Reactivity

Human

Immunogen

Recombinant human Centrosomal protein of 57 kDa protein (1-240AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

57 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:353245( Cow), Entrez Gene:9702( Human), Entrez Gene:74360( Mouse), Entrez Gene:315423( Rat), Omim:607951( Human), SwissProt:Q865V0( Cow), SwissProt:Q86XR8( Human), SwissProt:Q8CEE0( Mouse), SwissProt:B4F7A7( Rat), Unigene:101014( Human), Unigene:157212( Mouse), Unigene:94972( Rat)

Protein function

Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1. .

Protein tissue specificity

Ubiquitous. .

Involvement in disease

Mosaic variegated aneuploidy syndrome 2 (MVA2) [MIM:614114]: A severe developmental disorder characterized by mosaic aneuploidies, predominantly trisomies and monosomies, involving multiple different chromosomes and tissues. Affected individuals typically present with severe intrauterine growth retardation and microcephaly. Eye anomalies, mild dysmorphism, variable developmental delay, and a broad spectrum of additional congenital abnormalities and medical conditions may also occur. The risk of malignancy is high, with rhabdomyosarcoma, Wilms tumor and leukemia reported in several cases. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the translokin family. The C-terminal region mediates the interaction with microtubules and is able to nucleate and bundles microtubules in vitro.; The centrosome localization domain (CLD) region mediates the localization to centrosomes and homooligomerization.

Protein cellular localization

Nucleus . Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Research area

All research areas>Signaling Intermediates>CEP
(View all antibody categories related to Signaling Intermediates)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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