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Rabbit Anti-CHIA Antibody (CSB-PA874858ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Acidic mammalian chitinase Antibody,AMCase Antibody,Lung-specific protein TSA1902 Antibody,CHIA AntibodyMore alternative names for the antibody
Recommended applications: ELISA, WB, IHC
Recommended dilution: User optimized
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Acidic mammalian chitinase protein (1-368AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding. .
|Protein tissue specificity|| |
Detected in lung epithelial cells from asthma patients (at protein level). Highly expressed in stomach. Detected at lower levels in lung. .
|Protein sequence and domain|| |
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
|Protein cellular localization|| |
Isoform 1: Secreted. Note=Secretion depends on EGFR activity.; Isoform 2: Cytoplasm.; Isoform 3: Cytoplasm.
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CUSABIO BIOTECH CO.
|Product type|| |
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