Anti-CHMP1B Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-CHMP1B Antibody (CSB-PA748726ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

CHMP1.5 Antibody,Chromatin-modifying protein 1b Antibody, CHMP1b Antibody,Vacuolar protein sorting-associated protein 46-2 Antibody,Vps46-2 Antibody,hVps46-2 Antibody,CHMP1B Antibody,C18orf2 Antibody

More alternative names for the antibody
2810405I11Rik antibody|C10orf2 antibody|C18 ORF2 antibody|C18orf2 antibody|Charged multivesicular body protein 1b antibody|CHM1B_HUMAN antibody|CHMP family, member 1B antibody|CHMP1.5 antibody|CHMP1b antibody|Choromosome 18 open reading frame 2 antibody|Chromatin-modifying protein 1b antibody|hVps46-2 antibody|vacuolar protein sorting 46-2 antibody|Vacuolar protein sorting-associated protein 46-2 antibody|Vps46-2 antibody|Vps46B antibody
Anti-CHMP1B antibody – C-terminal (ab204749)
Close sc-69547|sc-514013|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-CHMP1B Antibody

Catalogue No.

CSB-PA748726ESR2HU

Reactivity

Human

Immunogen

Recombinant human Charged multivesicular body protein 1b protein (1-199AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

22 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:422143( Chicken), Entrez Gene:512033( Cow), Entrez Gene:57132( Human), Entrez Gene:67064( Mouse), Entrez Gene:689364( Rat), Entrez Gene:379412( Xenopus laevis), Entrez Gene:448582( Xenopus tropicalis ), Entrez Gene:336426( Zebrafish), Omim:606486( Human), SwissProt:Q5ZKX1( Chicken), SwissProt:Q5E994( Cow), SwissProt:Q7LBR1( Human), SwissProt:Q99LU0( Mouse), SwissProt:Q7SZB5( Xenopus laevis), SwissProt:Q6DF27( Xenopus tropicalis ), SwissProt:Q7ZVB1( Zebrafish), Unigene:656244( Human), Unigene:73777( Mouse), Unigene:39132( Rat), Unigene:7037( Xenopus laevis), Unigene:8435( Zebrafish)

Protein function

Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B and SPAST to the midbody of dividing cells. Involved in HIV-1 p6- and p9-dependent virus release. .

Protein tissue specificity

Widely expressed. Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta and brain. .

Protein sequence and domain

Belongs to the SNF7 family.

Protein cellular localization

Cytoplasm, cytosol. Endosome. Late endosome membrane ; Peripheral membrane protein . Note=Localizes to the midbody of dividing cells, colocalizing with CEP55 and CHMP5. Localized at the periphery of the Fleming body.

Research area

All research areas>Signaling Intermediates>CHMP
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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