Anti-CHRNG Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-CHRNG Antibody (CSB-PA005401ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Acetylcholine receptor subunit gamma Antibody,CHRNG Antibody,ACHRG Antibody

More alternative names for the antibody
Acetylcholine receptor muscle gamma subunit antibody|Acetylcholine receptor protein gamma chain precursor antibody|Acetylcholine receptor subunit gamma antibody|ACHG antibody|ACHG_HUMAN antibody|Achr 3 antibody|AChR antibody|Achr3 antibody|ACHRG antibody|ACRG antibody|Cholinergic receptor nicotinic gamma antibody|Cholinergic receptor nicotinic gamma polypeptide antibody|CHRNG antibody|MGC133376 antibody
Anti-Nicotinic Acetylcholine Receptor gamma antibody [66] (ab24667)
Close sc-58597|sc-1453|sc-13998|

Recommended applications: ELISA, WB

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-CHRNG Antibody

Catalogue No.

CSB-PA005401ESR2HU

Reactivity

Human

Immunogen

Recombinant human Acetylcholine receptor subunit gamma protein (328-517AA)

Host

Rabbit

Applications

ELISA, WB

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

57 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:1146( Human), Omim:100730( Human), SwissProt:P13536( Cow), SwissProt:P07510( Human), Unigene:248101( Human)

Protein function

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Involvement in disease

Multiple pterygium syndrome, lethal type (LMPS) [MIM:253290]: Multiple pterygia are found infrequently in children with arthrogryposis and in fetuses with fetal akinesia syndrome. In lethal multiple pterygium syndrome there is intrauterine growth retardation, multiple pterygia, and flexion contractures causing severe arthrogryposis and fetal akinesia. Subcutaneous edema can be severe, causing fetal hydrops with cystic hygroma and lung hypoplasia. Oligohydramnios and facial anomalies are frequent. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Multiple pterygium syndrome, Escobar variant (EVMPS) [MIM:265000]: Non-lethal form of arthrogryposis multiplex congenita. It is an autosomal recessive condition characterized by excessive webbing (pterygia), congenital contractures (arthrogryposis), and scoliosis. Variable other features include intrauterine death, congenital respiratory distress, short stature, faciocranial dysmorphism, ptosis, low-set ears, arachnodactyly and cryptorchism in males. Congenital contractures are common and may be caused by reduced fetal movements at sensitive times of development. Possible causes of decreased fetal mobility include space constraints such as oligohydramnion, drugs, metabolic conditions or neuromuscular disorders including myasthenia gravis. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Gamma/CHRNG sub-subfamily.

Protein cellular localization

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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