Anti-CIAPIN1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-CIAPIN1 Antibody (CSB-PA738750ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Anamorsin Antibody,Cytokine-induced apoptosis inhibitor 1 Antibody,CIAPIN1 Antibody

More alternative names for the antibody
2810413N20Rik antibody|Anamorsin antibody|CIAPIN 1 antibody|CIAPIN1 antibody|CPIN1_HUMAN antibody|Cytokine induced apoptosis inhibitor 1 antibody|Cytokine-induced apoptosis inhibitor 1 antibody|DRE2 antibody|Fe-S cluster assembly protein DRE2 homolog antibody|Predicted protein of HQ0915 antibody|PRO0915 antibody
Anti-CIAPIN1 antibody (ab154904)
Close sc-271298|sc-134449|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-CIAPIN1 Antibody

Catalogue No.

CSB-PA738750ESR1HU

Reactivity

Human

Immunogen

Recombinant human Anamorsin protein (1-312AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

33 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:57019( Human), Entrez Gene:109006( Mouse), Omim:608943( Human), SwissProt:Q6FI81( Human), SwissProt:Q8WTY4( Mouse), Unigene:4900( Human), Unigene:27582( Mouse), Unigene:472546( Mouse)

Protein function

Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity). Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Electrons are transferred to the Fe-S cluster from NADPH via the FAD- and FMN-containing protein NDOR1. .

Protein tissue specificity

Ubiquitously expressed. Highly expressed in heart, liver and pancreas. .

Protein sequence and domain

Belongs to the anamorsin family. The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine.; The C-terminal domain binds one 2Fe-2S iron-sulfur cluster but is otherwise mostly in an intrinsically disordered conformation.; The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

Protein cellular localization

Cytoplasm. Nucleus. Mitochondrion. Mitochondrion intermembrane space . Note=Imported into mitochondria (in vitro).

Research area

All research areas>Tumor Suppressor/Apoptosis>Anamorsin
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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