Anti-CLASP1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-CLASP1 Antibody (CSB-PA770347ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

CLIP-associating protein 1 Antibody,Cytoplasmic linker-associated protein 1 Antibody,Multiple asters homolog 1 Antibody,Protein Orbit homolog 1 Antibody,hOrbit1 Antibody,CLASP1 Antibody,KIAA0622 Antibody,MAST1 Antibody

More alternative names for the antibody
1700030C23Rik antibody|5730583A19Rik antibody|B130045P17Rik antibody|CLAP1_HUMAN antibody|clasp1 antibody|CLIP associating protein 1 antibody|CLIP associating protein CLASP1 antibody|CLIP-associating protein 1 antibody|Cytoplasmic linker associated protein 1 antibody|Cytoplasmic linker-associated protein 1 antibody|DKFZp686D1968 antibody|DKFZp686H2039 antibody|FLJ33821 antibody|FLJ41222 antibody|hOrbit1 antibody|KIAA0622 antibody|MAST1 antibody|MGC131895 antibody|mKIAA0622 antibody|Multiple asters 1 antibody|Multiple asters homolog 1 antibody|Protein Orbit homolog 1 antibody
Anti-CLASP1 antibody [EPR3409] (ab108620)
Close sc-390159|sc-33474|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-CLASP1 Antibody

Catalogue No.

CSB-PA770347ESR1HU

Reactivity

Human

Immunogen

Recombinant human CLIP-associating protein 1 protein (1389-1538AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

169 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:23332( Human), Entrez Gene:76707( Mouse), Entrez Gene:304740( Rat), Omim:605852( Human), SwissProt:Q7Z460( Human), SwissProt:Q80TV8( Mouse), Unigene:469840( Human), Unigene:708183( Human), Unigene:138740( Mouse)

Protein function

Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle. .

Protein sequence and domain

Belongs to the CLASP family.

Protein cellular localization

Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Golgi apparatus, trans-Golgi network . Note=Localizes to microtubule plus ends. Localizes to centrosomes, kinetochores and the mitotic spindle from prometaphase. Subsequently localizes to the spindle midzone from anaphase and to the midbody from telophase. In migrating cells localizes to the plus ends of microtubules within the cell body and to the entire microtubule lattice within the lamella. Localizes to the cell cortex and this requires ERC1 and PHLDB2.

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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