Anti-CLCN7 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-CLCN7 Antibody (CSB-PA005486ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

H(+)/Cl(-) exchange transporter 7 Antibody,Chloride channel 7 alpha subunit Antibody,Chloride channel protein 7 Antibody,ClC-7 Antibody,CLCN7 Antibody

More alternative names for the antibody
Chloride channel protein 7 antibody|CLC 7 antibody|ClC-7 antibody|ClC7 antibody|CLCN7 antibody|CLCN7_HUMAN antibody|FLJ26686 antibody|FLJ39644 antibody|FLJ46423 antibody|H(+)/Cl(-) exchange transporter 7 antibody|OPTA2 antibody|OPTB4 antibody
Anti-CLC7 antibody – C-terminal (ab170502)
Close sc-517044|sc-16444|sc-28755|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-CLCN7 Antibody

Catalogue No.

CSB-PA005486ESR1HU

Reactivity

Human

Immunogen

Recombinant human H(+)/Cl(-) exchange transporter 7 protein (626-805AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

88 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:1186( Human), Omim:602727( Human), SwissProt:P51798( Human), Unigene:459649( Human)

Protein function

Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen. .

Protein tissue specificity

Brain, testis, muscle and kidney.

Involvement in disease

Osteopetrosis, autosomal recessive 4 (OPTB4) [MIM:611490]: A rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. Osteopetrosis occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Recessive osteopetrosis commonly manifests in early infancy with macrocephaly, feeding difficulties, evolving blindness and deafness, bone marrow failure, severe anemia, and hepatosplenomegaly. Deafness and blindness are generally thought to represent effects of pressure on nerves. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Osteopetrosis, autosomal dominant 2 (OPTA2) [MIM:166600]: A rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. Osteopetrosis occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood. It is characterized by sclerosis, predominantly involving the spine, the pelvis and the skull base. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Osteopetrosis, autosomal recessive 2 (OPTB2) [MIM:259710]: A rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. Osteopetrosis occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Recessive osteopetrosis commonly manifests in early infancy with macrocephaly, feeding difficulties, evolving blindness and deafness, bone marrow failure, severe anemia, and hepatosplenomegaly. Deafness and blindness are generally thought to represent effects of pressure on nerves. OPTB2 is characterized by paucity of osteoclasts, suggesting a molecular defect in osteoclast development. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the chloride channel (TC 2.A.49) family. ClC-7/CLCN7 subfamily.

Protein cellular localization

Lysosome membrane ; Multi-pass membrane protein .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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