Anti-CLEC12A Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-CLEC12A Antibody (CSB-PA725176ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

C-type lectin-like molecule 1 Antibody,CLL-1 Antibody,Dendritic cell-associated lectin 2 Antibody,DCAL-2 Antibody,Myeloid inhibitory C-type lectin-like receptor Antibody,MICL Antibody,CLEC12A Antibody,CLL1 Antibody, DCAL2 Antibody, MICL Antibody

More alternative names for the antibody
C-type lectin domain family 12 member A antibody|C-type lectin-like molecule 1 antibody|CL12A_HUMAN antibody|CLEC12A antibody|CLL-1 antibody|DCAL-2 antibody|Dendritic cell-associated lectin 2 antibody|MICL antibody|Myeloid inhibitory C-type lectin-like receptor antibody
Anti-CLEC12A antibody (ab107494)
Close sc-109517|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-CLEC12A Antibody

Catalogue No.

CSB-PA725176ESR2HU

Reactivity

Human

Immunogen

Recombinant human C-type lectin domain family 12 member A protein (66-265AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

30 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:160364( Human), Omim:612088( Human), SwissProt:Q5QGZ9( Human), Unigene:190519( Human)

Protein function

Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. .

Protein tissue specificity

Detected in normal myeloid cells and in acute myeloid leukemia cells. Detected in neutrophils, eosinophils, monocytes and dendritic cells. Detected in spleen macrophage-rich red pulp and in lymph node (at protein level). Detected in peripheral blood leukocytes, dendritic cells, bone marrow, monocytes, mononuclear leukocytes and macrophages. .

Protein sequence and domain

Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.

Protein post-translational modifications

Highly N-glycosylated. Glycosylation varies between cell types. .

Protein cellular localization

Cell membrane ; Single-pass type II membrane protein . Note=Ligand binding leads to internalization.

Research area

All research areas>Lymphocyte Signaling>CLEC
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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