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Rabbit Anti-CLIC1 Antibody (CSB-PA005545ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Chloride channel ABP Antibody,Nuclear chloride ion channel 27 Antibody,NCC27 Antibody,Regulatory nuclear chloride ion channel protein Antibody,hRNCC Antibody,CLIC1 Antibody,G6 Antibody,NCC27 AntibodyMore alternative names for the antibody
Chloride channel ABP antibody|Chloride intracellular channel 1 antibody|Chloride intracellular channel protein 1 antibody|CLIC 1 antibody|CLIC1 antibody|CLIC1_HUMAN antibody|G6 antibody|hRNCC antibody|NCC 27 antibody|NCC27 antibody|Nuclear chloride ion channel 27 antibody|Nuclear chloride ion channel protein antibody|p64CLCP antibody|Regulatory nuclear chloride ion channel protein antibody|RNCC protein antibody
Anti-CLIC1 antibody (ab77214)
Anti-CLIC1 antibody (ab77214)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:500-5000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Chloride intracellular channel protein 1 protein (42-241AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:515646( Cow), Entrez Gene:1192( Human), Entrez Gene:114584( Mouse), Entrez Gene:406864( Rat), Omim:602872( Human), SwissProt:Q5E9B7( Cow), SwissProt:O00299( Human), SwissProt:Q9Z1Q5( Mouse), SwissProt:Q95MF9( Rabbit), SwissProt:Q6MG61( Rat), Unigene:414565( Human), Unigene:29524( Mouse), Unigene:203139( Rat)
|Protein function|| |
Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle. .
|Protein tissue specificity|| |
Expression is prominent in heart, placenta, liver, kidney and pancreas. .
|Protein sequence and domain|| |
Belongs to the chloride channel CLIC family. Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
|Protein post-translational modifications|| |
Hydrogen peroxide treatment causes a conformation change, leading to dimerization and formation of an intramolecular disulfide bond between Cys-24 and Cys-59.
|Protein cellular localization|| |
Nucleus. Nucleus membrane ; Single-pass membrane protein . Cytoplasm. Cell membrane ; Single-pass membrane protein . Note=Mostly in the nucleus including in the nuclear membrane. Small amount in the cytoplasm and the plasma membrane. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.
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CUSABIO BIOTECH CO.
|Product type|| |
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