Anti-CNGA3 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-CNGA3 Antibody (CSB-PA613670DSR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Cyclic nucleotide-gated cation channel alpha-3 Antibody,Cone photoreceptor cGMP-gated channel subunit alpha Antibody,Cyclic nucleotide-gated channel alpha-3 Antibody,CNG channel alpha-3 Antibody,CNG-3 Antibody,CNG3 Antibody,CNGA3 Antibody,CNCG3 Antibody

More alternative names for the antibody
ACHM2 antibody|CCNC1 antibody|CCNCa antibody|CCNCalpha antibody|CNCG3 antibody|CNG 3 antibody|CNG channel alpha 3 antibody|CNG channel alpha-3 antibody|CNG-3 antibody|CNG3 antibody|CNGA3 antibody|Cnga3 cyclic nucleotide gated channel alpha 3 antibody|CNGA3_HUMAN antibody|Cone photoreceptor cGMP gated channel antibody|Cone photoreceptor cGMP gated channel alpha subunit antibody|Cone photoreceptor cGMP gated channel subunit alpha antibody|Cone photoreceptor cGMP-gated channel subunit alpha antibody|Cyclic nucleotide gated cation channel alpha 3 antibody|Cyclic nucleotide gated channel alpha 3 antibody|Cyclic nucleotide gated channel olfactory 3 antibody|Cyclic nucleotide gated channel rod photoreceptor subunit alpha antibody|Cyclic nucleotide-gated cation channel alpha-3 antibody|Cyclic nucleotide-gated channel alpha-3 antibody|OTTHUMP00000161120 antibody
Anti-CNG3 antibody (ab97500)
Close

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-CNGA3 Antibody

Catalogue No.

CSB-PA613670DSR1HU

Reactivity

Human

Immunogen

Recombinant human Cyclic nucleotide-gated cation channel alpha-3 protein (1-165AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

78 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:1261( Human), Omim:600053( Human), SwissProt:Q29441( Cow), SwissProt:Q16281( Human), Unigene:234785( Human)

Protein function

Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones. .

Protein tissue specificity

Prominently expressed in retina.

Involvement in disease

Achromatopsia 2 (ACHM2) [MIM:216900]: An ocular stationary disorder due to the absence of functioning cone photoreceptors in the retina. It is characterized by total colorblindness, low visual acuity, photophobia and nystagmus. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA3 subfamily. The C-terminal coiled-coil domain mediates homotrimerization of CNGA subunits.

Protein cellular localization

Membrane; Multi-pass membrane protein.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!