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Rabbit Anti-CNTNAP1 Antibody (CSB-PA005692ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Contactin-associated protein 1 Antibody,Caspr Antibody,Caspr1 Antibody,Neurexin IV Antibody,Neurexin-4 Antibody,p190 Antibody,CNTNAP1 Antibody,CASPR Antibody,NRXN4 AntibodyMore alternative names for the antibody
Caspr antibody|Caspr1 antibody|CNTNAP antibody|Cntnap1 antibody|CNTP1_HUMAN antibody|Contactin associated protein 1 antibody|Contactin-associated protein 1 antibody|MHDNIV antibody|NCP1 antibody|Neurexin 4 antibody|Neurexin IV antibody|Neurexin-4 antibody|Nrxn4 antibody|p190 antibody|Paranodin antibody
Anti-Caspr antibody (ab34151)
Anti-Caspr antibody (ab34151)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Contactin-associated protein 1 protein (20-300AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:8506( Human), Entrez Gene:53321( Mouse), Entrez Gene:84008( Rat), Omim:602346( Human), SwissProt:P78357( Human), SwissProt:O54991( Mouse), SwissProt:P97846( Rat), Unigene:408730( Human), Unigene:474527( Mouse), Unigene:88654( Rat)
|Protein function|| |
Seems to play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the paranodal region of the axo-glial junction. In association with contactin may have a role in the signaling between axons and myelinating glial cells.
|Protein tissue specificity|| |
Predominantly expressed in brain. Weak expression detected in ovary, pancreas, colon, lung, heart, intestine and testis.
|Involvement in disease|| |
Lethal congenital contracture syndrome 7 (LCCS7) [MIM:616286]: A form of lethal congenital contracture syndrome, an autosomal recessive disorder characterized by degeneration of anterior horn neurons, extreme skeletal muscle atrophy and congenital non-progressive joint contractures. The contractures can involve the upper or lower limbs and/or the vertebral column, leading to various degrees of flexion or extension limitations evident at birth. LCCS7 is a severe axoglial disease characterized by congenital distal joint contractures, polyhydramnios, reduced fetal movements, and motor paralysis leading to death early in the neonatal period. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the neurexin family.
|Protein cellular localization|| |
Membrane ; Single-pass type I membrane protein .
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CUSABIO BIOTECH CO.
|Product type|| |
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