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Rabbit Anti-COCH Antibody (CSB-PA005703ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Cochlin Antibody,COCH-5B2 Antibody,COCH Antibody,COCH5B2 Antibody,UNQ257/PRO294 AntibodyMore alternative names for the antibody
Coagulation factor C homolog, cochlin (Limulus polyphemus) antibody|COCH antibody|COCH-5B2 antibody|COCH_HUMAN antibody|COCH5B2 antibody|Cochlin antibody|DFNA9 antibody
Anti-COCH antibody (ab171410)
Anti-COCH antibody (ab171410)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Cochlin protein (20-260AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1690" target="_blank">Entrez Gene:1690( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/603196" target="_blank">Omim:603196( Human)</a>, <a href="http://www.uniprot.org/uniprot/O43405" target="_blank">SwissProt:O43405( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=21016" target="_blank">Unigene:21016( Human)</a>
|Protein function|| |
Plays a role in the control of cell shape and motility in the trabecular meshwork. .
|Protein tissue specificity|| |
Expressed in inner ear structures; the cochlea and the vestibule.
|Involvement in disease|| |
Deafness, autosomal dominant, 9 (DFNA9) [MIM:601369]: A form of non-syndromic hearing loss characterized by onset in the fourth or fifth decade of life and initially involves the high frequencies. Hearing loss is progressive and usually complete by the sixth decade. In addition to cochlear involvement, DFNA9 patients also exhibit a spectrum of vestibular dysfunctions. Penetrance of the vestibular symptoms is often incomplete, and some patients are minimally affected, whereas others suffer from severe balance disturbances and episodes of vertigo. Affected individuals have mucopolysaccharide depositions in the channels of the cochlear and vestibular nerves. These depositions apparently cause strangulation and degeneration of dendritic fibers. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein post-translational modifications|| |
N-glycosylated. .; A 50 kDa form is created by proteolytic cleavage. .
|Protein cellular localization|| |
Secreted, extracellular space, extracellular matrix .
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Structural-Proteins/">Structural Proteins</a>><a href="https://antibodyplus.com/product-tag/Cochlin/">Cochlin</a><br><a href="https://antibodyplus.com/product-tag/Structural-Proteins/"> (View all antibody categories related to Structural Proteins)</a>
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CUSABIO BIOTECH CO.
|Product type|| |
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