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Rabbit Anti-COPS2 Antibody (CSB-PA005789ESR2HU)
Supplier: CUSABIO BIOTECH CO.
SGN2 Antibody,Signalosome subunit 2 Antibody,Alien homolog Antibody,JAB1-containing signalosome subunit 2 Antibody,Thyroid receptor-interacting protein 15 Antibody,TR-interacting protein 15 Antibody,TRIP-15 Antibody,COPS2 Antibody,CSN2 Antibody,TRIP15 AntibodyMore alternative names for the antibody
ALIEN antibody|Alien Drosophila himolog of antibody|Alien homolog antibody|COP 9 antibody|COP9 antibody|COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) antibody|COP9 constitutive photomorphogenic homolog subunit 2 antibody|COP9 signalosome complex subunit 2 antibody|COPS 2 antibody|Cops2 antibody|CSN2 antibody|CSN2_HUMAN antibody|JAB1 containing signalosome subunit 2 antibody|JAB1-containing signalosome subunit 2 antibody|SGN 2 antibody|SGN2 antibody|Signalosome subunit 2 antibody|Thyroid Hormone Receptor Interactor15 antibody|Thyroid Hormone Receptor Interactor 15 antibody|Thyroid receptor-interacting protein 15 antibody|TR-interacting protein 15 antibody|TRIP 15 antibody|TRIP-15 antibody|TRIP15 antibody
Anti-TRIP15 antibody (ab155774)
Anti-TRIP15 antibody (ab155774)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human COP9 signalosome complex subunit 2 protein (1-310AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:430917( Chicken), Entrez Gene:9318( Human), Entrez Gene:12848( Mouse), Entrez Gene:100125956( Pig), Entrez Gene:261736( Rat), Entrez Gene:548537( Xenopus tropicalis ), Omim:604508( Human), SwissProt:P61201( Human), SwissProt:P61202( Mouse), SwissProt:P61203( Rat), SwissProt:Q6IR75( Xenopus laevis), Unigene:369614( Human), Unigene:3596( Mouse), Unigene:11556( Rat), Unigene:83155( Xenopus laevis)
|Protein function|| |
Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1. .
|Protein sequence and domain|| |
Belongs to the CSN2 family.
|Protein post-translational modifications|| |
Phosphorylated by CK2 and PKD kinases. .
|Protein cellular localization|| |
Cytoplasm . Nucleus .
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CUSABIO BIOTECH CO.
|Product type|| |
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