Anti-COPS2 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-COPS2 Antibody (CSB-PA005789ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

SGN2 Antibody,Signalosome subunit 2 Antibody,Alien homolog Antibody,JAB1-containing signalosome subunit 2 Antibody,Thyroid receptor-interacting protein 15 Antibody,TR-interacting protein 15 Antibody,TRIP-15 Antibody,COPS2 Antibody,CSN2 Antibody,TRIP15 Antibody

More alternative names for the antibody
ALIEN antibody|Alien Drosophila himolog of antibody|Alien homolog antibody|COP 9 antibody|COP9 antibody|COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) antibody|COP9 constitutive photomorphogenic homolog subunit 2 antibody|COP9 signalosome complex subunit 2 antibody|COPS 2 antibody|Cops2 antibody|CSN2 antibody|CSN2_HUMAN antibody|JAB1 containing signalosome subunit 2 antibody|JAB1-containing signalosome subunit 2 antibody|SGN 2 antibody|SGN2 antibody|Signalosome subunit 2 antibody|Thyroid Hormone Receptor Interactor15 antibody|Thyroid Hormone Receptor Interactor 15 antibody|Thyroid receptor-interacting protein 15 antibody|TR-interacting protein 15 antibody|TRIP 15 antibody|TRIP-15 antibody|TRIP15 antibody
Anti-TRIP15 antibody (ab155774)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-COPS2 Antibody

Catalogue No.

CSB-PA005789ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human COP9 signalosome complex subunit 2 protein (1-310AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

51 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:430917( Chicken), Entrez Gene:9318( Human), Entrez Gene:12848( Mouse), Entrez Gene:100125956( Pig), Entrez Gene:261736( Rat), Entrez Gene:548537( Xenopus tropicalis ), Omim:604508( Human), SwissProt:P61201( Human), SwissProt:P61202( Mouse), SwissProt:P61203( Rat), SwissProt:Q6IR75( Xenopus laevis), Unigene:369614( Human), Unigene:3596( Mouse), Unigene:11556( Rat), Unigene:83155( Xenopus laevis)

Protein function

Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1. .

Protein sequence and domain

Belongs to the CSN2 family.

Protein post-translational modifications

Phosphorylated by CK2 and PKD kinases. .

Protein cellular localization

Cytoplasm . Nucleus .

Research area

All research areas>Signaling Intermediates>TRIP15
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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