Anti-COPS3 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC,IP
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-COPS3 Antibody (CSB-PA892483ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

COP9 signalosome complex subunit 3 Antibody,SGN3 Antibody,Signalosome subunit 3 Antibody,JAB1-containing signalosome subunit 3 Antibody,COPS3 Antibody,CSN3 Antibody

More alternative names for the antibody
Constitutive photomorphogenic homolog subunit 3 antibody|COP 9 (constitutive photomorphogenic) subunit 3 antibody|COP 9 complex homolog subunit 3 antibody|COP 9 complex S3 antibody|COP 9 complex subunit 3 antibody|COP 9 constitutive photomorphogenic homolog subunit 3 antibody|COP 9 homolog antibody|COP 9 signalosome complex subunit 3 antibody|COP 9 signalosome subunit 3 antibody|COP 9 subunit 3 antibody|COP9 (constitutive photomorphogenic) subunit 3 antibody|COP9 complex homolog subunit 3 antibody|COP9 complex S3 antibody|COP9 complex subunit 3 antibody|COP9 constitutive photomorphogenic homolog subunit 3 antibody|COP9 homolog antibody|COP9 signalosome complex subunit 3 antibody|COP9 signalosome subunit 3 antibody|COP9 subunit 3 antibody|COPS 3 antibody|cops3 antibody|CSN 3 antibody|CSN3 antibody|CSN3_HUMAN antibody|JAB 1 containing signalosome subunit 3 antibody|JAB1 containing signalosome subunit 3 antibody|JAB1-containing signalosome subunit 3 antibody|SGN 3 antibody|SGN3 antibody|Signalosome subunit 3 antibody
Anti-COPS3 antibody [EPR3127] (ab79698)
Close sc-47961|sc-367529|sc-100693|

Recommended applications: ELISA, WB, IHC, IP

Recommended dilution: Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000

Recommended protocols: check protocols

Name

Anti-COPS3 Antibody

Catalogue No.

CSB-PA892483ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human COP9 signalosome complex subunit 3 protein (194-423AA)

Host

Rabbit

Applications

ELISA, WB, IHC, IP

Recommended dilution

Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

47 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:8533( Human), Entrez Gene:26572( Mouse), Entrez Gene:287367( Rat), Omim:604665( Human), SwissProt:Q9UNS2( Human), SwissProt:O88543( Mouse), SwissProt:Q68FW9( Rat), Unigene:6076( Human), Unigene:40( Mouse), Unigene:3963( Rat)

Protein function

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. .

Protein tissue specificity

Widely expressed. Expressed at high level in heart and skeletal muscle. .

Protein sequence and domain

Belongs to the CSN3 family.

Protein cellular localization

Cytoplasm . Nucleus .

Research area

All research areas>Signaling Intermediates>CSN
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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